Laparoscopy Reveals a Diversity of Peritoneal Change in Patients with Long-Term Vintage of Peritoneal Dialysis

被引:7
作者
Sasaki, Koichi [1 ,7 ]
Mizuno, Hitoshi [2 ]
Iwamoto, Noriyuki [3 ]
Imakita, Masami [4 ]
Yasuda, Keiko [5 ]
Kimura, Tomonori [5 ]
Rakugi, Hiromi [5 ]
Isaka, Yoshitaka [5 ]
Hayashi, Terumasa [6 ,7 ]
机构
[1] Osaka Hosp, Japan Community Hlth Care Org, Dept Nephrol, Osaka, Japan
[2] Osaka Hosp, Japan Community Hlth Care Org, Dept Surg, Osaka, Japan
[3] Tojinkai Hosp, Dept Urol, Kyoto, Japan
[4] Rinku Gen Med Ctr, Dept Pathol, Izumisano, Japan
[5] Osaka Univ, Grad Sch Med, Dept Geriatr Med & Nephrol, Suita, Osaka, Japan
[6] Osaka Gen Med Ctr, Dept Kidney Dis & Hypertens, Osaka, Japan
[7] Rinku Gen Med Ctr, Dept Nephrol, Izumisano, Japan
关键词
Acidic dialysate; Encapsulating peritoneal sclerosis; Laparoscopy; Peritoneal dialysis; Peritoneal equilibration test; SCLEROSING ENCAPSULATING PERITONITIS; SURGICAL-MANAGEMENT; SOLUTE TRANSPORT; JAPAN; MULTICENTER; DIAGNOSIS;
D O I
10.1159/000439241
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Although laparoscopy may provide more detailed morphological and histological information about peritoneal damage, its significance in patients with long vintage of peritoneal dialysis (PD) is not elucidated. Methods: Findings in 12 patients with PD vintage of 7.3 (5.0-8.4) years who had undergone laparoscopy between 2007 and 2011 were reviewed. Macroscopic (peritoneal change, hypervascular change, adhesion, encapsulation) and histopathological peritoneal findings (interstitial fibrosis, microvascular change, fibrin deposition, inflammatory cell infiltration) were scored and summed as Macro-total score (Macro-TS) and Micro-total score (Micro-TS), respectively. Factors associated with these scores and the relationship between these scores were investigated. Results: Neither Macro-TS nor Micro-TS were related to PD vintage (p = 0.069 and p = 0.769, respectively); moreover, Macro-TS varied from patient to patient regardless of similar PD vintage. However, Macro-TS showed a significant association with duration of acidic dialysate (p = 0.003). Conclusion: Macroscopic and microscopic findings via laparoscopy may help the assessment of peritoneal damage in patients with long PD vintage. (C) 2015 S. Karger AG, Basel
引用
收藏
页码:48 / 54
页数:7
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