An efficient method for the synthesis of 2,4,5-trisubstituted imidazoles using lactic acid as promoter

被引：13

作者：

Sonar, Jayant ^{[1
]}

Pardeshi, Sandeep ^{[1
]}

Dokhe, Shrikant ^{[1
]}

Pawar, Rajendra ^{[4
]}

Kharat, Kiran ^{[5
]}

Zine, Ashok ^{[2
]}

Matsagar, Babasaheb ^{[3
]}

Wu, Kevin ^{[3
]}

Thore, Shivaji ^{[4
]}

机构：

[1] Vinayakrao Patil Mahavidyalaya, Dept Chem, Aurangabad 423701, Maharashtra, India

[2] Sunderrao Solunke Mahavidyalaya, Dept Chem, Majalgaon 431131, Maharashtra, India

[3] Natl Taiwan Univ, Chem Engn Dept, Taipei 106, Taiwan

[4] Deogiri Coll, Dept Chem, Stn Rd, Aurangabad 431005, Maharashtra, India

[5] Deogiri Coll, Dept Biotechnol, Stn Rd, Aurangabad 431005, Maharashtra, India

来源：

SN APPLIED SCIENCES | 2019年 / 1卷 / 09期

关键词：

Lactic acid; Promotor; Green solvent; 2,4,5-Trisubstituted imidazoles; DERIVATIVES; CATALYST;

D O I：

10.1007/s42452-019-0935-0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Synthesis of 2,4,5-trisubstituted imidazole compounds from an aromatic aldehyde, benzil and ammonium acetate is demonstrated using biodegradable lactic acid at 160 degrees C. This method is a simple, environmentally benign, and works for aromatic aldehyde containing electron donating and electron withdrawing groups. [GRAPHICS] .

引用

页数：7

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