Natural dibenzoxazepinones from leaves of Carex distachya:: Structural elucidation and radical scavenging activity

被引：32

作者：

Fiorentino, Antonio ^{[1
]}

D'Abrosca, Brigida ^{[1
]}

Pacifico, Severina ^{[1
]}

Cefarelli, Giuseppe ^{[1
]}

Uzzo, Piera ^{[1
]}

Monaco, Pietro ^{[1
]}

机构：

[1] Univ Naples 2, Dipartimento Sci Vita, I-81100 Caserta, Italy

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2007年 / 17卷 / 03期

关键词：

dibenzoxazepinones; Carex distachya; spectroscopic analysis; radical scavenging activity;

D O I：

10.1016/j.bmcl.2006.11.002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new dibenzoxazepinones have been isolated from the leaves of Carex distachya, an herbaceous plant growing in the Mediterranean area. The structures have been elucidated on the basis of their spectroscopic properties. Bidimensional NMR (DQ-COSY, TOCSY, NOESY, ROESY, HSQC, and HMBC) furnished important data useful for the characterization of the molecules. The compounds have been assayed, for the antioxidant activity, by measuring its capacity to scavenge the DPPH, the superoxide anion, and nitric oxide radicals. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：636 / 639

页数：4

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