Management of Hyperglycemic Crises Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State

被引：138

作者：

Fayfman, Maya ^{[1
]}

Pasquel, Francisco J. ^{[1
]}

Umpierrez, Guillermo E. ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Dept Med, Div Endocrinol & Metab, 69 Jesse Hill Jr Dr Southeast,2nd Floor, Atlanta, GA 30303 USA

来源：

MEDICAL CLINICS OF NORTH AMERICA | 2017年 / 101卷 / 03期

关键词：

Hyperglycemic emergencies; Diabetic ketoacidosis; Hyperglycemic hyperosmolar state; Management of hyperglycemic emergencies; Diabetes; INTRAVENOUS REGULAR INSULIN; RETROSPECTIVE COHORT; BICARBONATE THERAPY; OXIDATIVE STRESS; CEREBRAL EDEMA; ADULT PATIENTS; KETONE-BODIES; TYPE-1; CHILDREN; RISK;

D O I：

10.1016/j.mcna.2016.12.011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are the most serious and life-threatening hyperglycemic emergencies in diabetes. DKA is more common in young people with type 1 diabetes and HHS in adult and elderly patients with type 2 diabetes. Features of the 2 disorders with ketoacidosis and hyperosmolality may coexist. Both are characterized by insulinopenia and severe hyperglycemia. Early diagnosis and management are paramount. Treatment is aggressive rehydration, insulin therapy, electrolyte replacement, and treatment of underlying precipitating events. This article reviews the epidemiology, pathogenesis, diagnosis, and management of hyperglycemic emergencies.

引用

页码：587 / +

页数：21

共 124 条

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