Interplay between NRF2 and GPX4 is critical for cancer cell survival in 3D spheroids

被引：0
作者：
Cho, Patricia [1 ]
Takahashi, Nobuaki [1 ]
Selfors, Laura M. [1 ]
Kuiken, Hendrik J. [1 ]
Brugge, Joan S. [1 ]
机构：
[1] Harvard Med Sch, Boston, MA 02115 USA
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-884
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
884
引用
收藏
页数：2
相关论文
共 50 条
[31]   Exploring the Mechanism of Ferroptosis Induction by Sappanone A in Cancer: Insights into the Mitochondrial Dysfunction Mediated by NRF2/xCT/GPX4 Axis [J].
Wang, Junyan ;
Zhuang, Haowen ;
Yang, Xiaocui ;
Guo, Zhijiang ;
Zhou, Kainan ;
Liu, Nanyang ;
An, Yang ;
Chen, Ye ;
Zhang, Zhongzheng ;
Wang, Mengyuan ;
Chen, Jinhong ;
Li, Chun ;
Chang, Xing .
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2024, 20 (13) :5145-5161
[32]   Estrogen deficiency accelerates postmenopausal atherosclerosis by inducing endothelial cell ferroptosis through inhibiting NRF2/GPX4 pathway [J].
Lv, Ying ;
Zhang, Shan ;
Weng, Xiuzhu ;
Huang, Jianxin ;
Zhao, Honggang ;
Dai, Xinyu ;
Bai, Xiaoxuan ;
Bao, Xiaoyi ;
Zhao, Chen ;
Zeng, Ming ;
Bai, Yunshu ;
Hu, Sining ;
Li, Ji ;
Jia, Haibo ;
Yu, Bo .
FASEB JOURNAL, 2023, 37 (06)
[33]   The induction of ferroptosis by impairing STAT3/Nrf2/GPx4 signaling enhances the sensitivity of osteosarcoma cells to cisplatin [J].
Liu, Qiang ;
Wang, Kunzheng .
CELL BIOLOGY INTERNATIONAL, 2019, 43 (11) :1245-1256
[34]   Electroacupuncture attenuates ferroptosis by promoting Nrf2 nuclear translocation and activating Nrf2/SLC7A11/GPX4 pathway in ischemic stroke [J].
Yang, Xi-chen ;
Jin, Ya-ju ;
Ning, Rong ;
Mao, Qiu-yue ;
Zhang, Peng-yue ;
Zhou, Li ;
Zhang, Cheng-cai ;
Peng, Yi-chen ;
Chen, Na .
CHINESE MEDICINE, 2025, 20 (01)
[35]   Resveratrol inhibits ferroptosis via activating NRF2/GPX4 pathway in mice with spinal cord injury [J].
Ni, Chengtao ;
Ye, Qing ;
Mi, Xiaodan ;
Jiao, Dian ;
Zhang, Shuangshuang ;
Cheng, Ruidong ;
Fang, Zhanglu ;
Fang, Marong ;
Ye, Xiangming .
MICROSCOPY RESEARCH AND TECHNIQUE, 2023, 86 (10) :1378-1390
[36]   Metabolic liabilities of iron-dependent ferroptosis mediated through NRF2/GPX4 axis in osteosarcoma [J].
Abdullah, Md ;
Lee, Donghee ;
Li, Rong ;
Kim, Jong Hyuk .
CANCER RESEARCH, 2024, 84 (06)
[37]   Nrf2 alleviates acute ischemic stroke induced ferroptosis via regulating xCT/GPX4 pathway [J].
Ye, Yujun ;
Xie, Xuexin ;
Bi, Yiming ;
Liu, Qing ;
Qiu, Lingling ;
Zhao, He ;
Wang, Chengyin ;
Zhu, Weifeng ;
Zeng, Ting .
FREE RADICAL BIOLOGY AND MEDICINE, 2025, 231 :153-162
[38]   Resveratrol inhibits ferroptosis via activating NRF2/GPX4 pathway in mice with spinal cord injury [J].
Risser, Bob .
PCI JOURNAL, 2023, 68 (03) :7-7
[39]   Orientin promotes diabetic wounds healing by suppressing ferroptosis via activation of the Nrf2/GPX4 pathway [J].
Yang, Jia-yi ;
Zhuang, Chen ;
Lin, Yu-zhe ;
Yu, Yi-tian ;
Zhou, Chen-cheng ;
Zhang, Chao-yang ;
Zhu, Zi-teng ;
Qian, Cheng-jie ;
Zhou, Yi-nan ;
Zheng, Wen-hao ;
Zhao, Yu ;
Jin, Chen ;
Wu, Zong-yi .
FOOD SCIENCE & NUTRITION, 2024, 12 (10) :7461-7480
[40]   Alliin mitigates the acute kidney injury by suppressing ferroptosis via regulating the Nrf2/GPX4 axis [J].
Jiang, Chunling ;
Huang, Huaying ;
Zhong, Chonghui ;
Feng, Songtao ;
Wang, Chunlei ;
Xue, Huajun ;
Zhang, Jing .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2025, 398 (02) :1521-1533
12345