Effects of obesity on the oxygen cost of breathing in children

被引：6

作者：

Bhammar, Dharini M. ^{[1
,2
,3
]}

Babb, Tony G. ^{[2
,3
]}

机构：

[1] Univ Nevada, Dept Kinesiol & Nutr Sci, Sch Integrated Hlth Sci, Las Vegas, NV 89154 USA

[2] Texas Hlth Presbyterian Hosp Dallas, Inst Exercise & Environm Med, Dallas, TX USA

[3] UT Southwestern Med Ctr, Dallas, TX USA

来源：

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY | 2021年 / 285卷

关键词：

Work of breathing; Pediatric obesity; Resting oxygen uptake; Ventilatory load;

D O I：

10.1016/j.resp.2020.103591

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The objective of this study was to examine the effects of obesity on the oxygen (O-2) cost of breathing using the eucapnic voluntary hyperpnea (EVH) technique in 10- and 11-year-old children. Seventeen children (8 without and 9 with obesity) underwent EVH trials at two levels of ventilation for assessing the O-2 cost of breathing (slope of oxygen uptake, VO2 vs. minute ventilation) and a dual energy x-ray absorptiometry scan. Resting and EVH VO2 was higher in children with obesity when compared with children without obesity (P = 0.0096). The O-2 cost of breathing did not statistically differ between children without (2.09 +/- 0.46 mL/L) and with obesity (2.08 +/- 0.64 mL/L, P = 0.99), but the intercept was significantly greater in children with obesity. Chest mass explained 85 % of the variance in resting VO2 in children with obesity. Higher resting energy requirements, attributable to increased chest mass, can increase the absolute metabolic costs of exercise and hyperpnea in children with obesity.

引用

页数：8