Evaluating the cytotoxicity of palladium/magnetite nano-catalysts intended for wastewater treatment

被引：37

作者：

Hildebrand, Heike ^{[1
]}

Kuehnel, Dana ^{[2
]}

Potthoff, Annegret ^{[3
]}

Mackenzie, Katrin ^{[1
]}

Springer, Armin ^{[4
]}

Schirmer, Kristin ^{[5
,6
]}

机构：

[1] UFZ Helmholtz Ctr Environm Res, Dept Environm Engn, D-04318 Leipzig, Germany

[2] UFZ Helmholtz Ctr Environm Res, Dept Bioanalyt Ecotoxicol, D-04318 Leipzig, Germany

[3] Fraunhofer IKTS, D-01277 Dresden, Germany

[4] Tech Univ Dresden, Inst Mat Sci, Max Bergmann Ctr Biomat, D-01069 Dresden, Germany

[5] Eawag Swiss Fed Inst Aquat Sci & Technol, CH-8600 Dubendorf, Switzerland

[6] ETH, Inst Biogeochem & Pollutant Dynam, CH-8092 Zurich, Switzerland

来源：

ENVIRONMENTAL POLLUTION | 2010年 / 158卷 / 01期

关键词：

Palladium-magnetite; Nano-catalysts; Magnetite; Cytotoxicity; ROS; NANOSCALE IRON PARTICLES; CELL-LINE; ESCHERICHIA-COLI; ZEROVALENT IRON; RAINBOW-TROUT; NANOPARTICLES; TOXICITY; CULTURE; HYDRODECHLORINATION; HYDRODEHALOGENATION;

D O I：

10.1016/j.envpol.2009.08.021

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Palladium/magnetite nanoparticulate catalysts were developed for efficient elimination of halogenated organic pollutants from contaminated wastewater. Particle recovery from treated water can be ensured via magnetic separation. However, in worst-case scenarios, this catalyst removal step might fail, leading to particle release into the environment. Therefore, a toxicological study was conducted to investigate the impact of both pure magnetite and palladium/magnetite nanoparticle exposure upon human skin (HaCaT) and human colon (CaCo-2) cell lines and a cell line from rainbow trout gills (RTgill-W1). To quantify cell viability after particle exposure, three endpoints were examined for all tested cell lines. Additionally, the formation of reactive oxygen species was studied for the human cells. The results showed only minor effects of the particles on the tested cell systems and support the assumption that palladium/magnetite nano-catalysts can be implemented for a new wastewater treatment technology in which advantageous catalyst properties outweigh the risks. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：65 / 73

页数：9

共 32 条

[1] Agglomeration and sedimentation of TiO2 nanoparticles in cell culture medium [J].

Allouni, Zouhir E. ;

Cimpan, Mihaela R. ;

Hol, Paul J. ;

Skodvin, Tore ;

Gjerdet, Nils R. .

COLLOIDS AND SURFACES B-BIOINTERFACES, 2009, 68 (01) :83-87

[2] Relation between the redox state of iron-based nanoparticles and their cytotoxicity toward Escherichia coli [J].

Auffan, Melanie ;

Achouak, Wafa ;

Rose, Jerome ;

Roncato, Marie-Anne ;

Chaneac, Corinne ;

Waite, David T. ;

Masion, Armand ;

Woicik, Joseph C. ;

Wiesner, Mark R. ;

Bottero, Jean-Yves .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2008, 42 (17) :6730-6735

[3] Toxicity of Tungsten Carbide and Cobalt-Doped Tungsten Carbide Nanoparticles in Mammalian Cells in Vitro [J].

Bastian, Susanne ;

Busch, Wibke ;

Kuehnel, Dana ;

Springer, Armin ;

Meissner, Tobias ;

Holke, Roland ;

Scholz, Stefan ;

Iwe, Maria ;

Pompe, Wolfgang ;

Gelinsky, Michael ;

Potthoff, Annegret ;

Richter, Volkmar ;

Ikonomidou, Chrysanthy ;

Schirmer, Kristin .

ENVIRONMENTAL HEALTH PERSPECTIVES, 2009, 117 (04) :530-536

[4] DEVELOPMENT OF A CELL-LINE FROM PRIMARY CULTURES OF RAINBOW-TROUT, ONCORHYRZCHUS MYKISS (WALBAUM), GILLS [J].

BOLS, NC ;

BARLIAN, A ;

CHIRINOTREJO, M ;

CALDWELL, SJ ;

GOEGAN, P ;

LEE, LEJ .

JOURNAL OF FISH DISEASES, 1994, 17 (06) :601-611

[5] NORMAL KERATINIZATION IN A SPONTANEOUSLY IMMORTALIZED ANEUPLOID HUMAN KERATINOCYTE CELL-LINE [J].

BOUKAMP, P ;

PETRUSSEVSKA, RT ;

BREITKREUTZ, D ;

HORNUNG, J ;

MARKHAM, A ;

FUSENIG, NE .

JOURNAL OF CELL BIOLOGY, 1988, 106 (03) :761-771

[6] Biological control of the size and reactivity of catalytic Pd(0) produced by Shewanella oneidensis [J].

De Windt, Wim ;

Boon, Nico ;

Van den Bulcke, Jan ;

Rubberecht, Leen ;

Prata, Filipa ;

Mast, Jan ;

Hennebel, Tom ;

Verstraete, Willy .

ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 2006, 90 (04) :377-389

[7]

*DIN, 1972, 53206 DIN

[8]

*DIN ISO, 2004, 13321 DIN ISO

[9] Functional toxicity and tolerance patterns of bioavailable Pd(II), Pt(II), and Rh(III) on suspended Saccharomyces cerevisiae cells assayed in tandem by a respirometric biosensor [J].

Frazzoli, Chiara ;

Dragone, Roberto ;

Mantovani, Alberto ;

Massimi, Cristiana ;

Campanella, Luigi .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2007, 389 (7-8) :2185-2194

[10] Measuring reactive species and oxidative damage in vivo and in cell culture:: how should you do it and what do the results mean? [J].

Halliwell, B ;

Whiteman, M .

BRITISH JOURNAL OF PHARMACOLOGY, 2004, 142 (02) :231-255

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