Ultrastructural localization of neuronal nitric oxide synthase immunoreactivity in the rat ileum

被引：34

作者：

Matini, P ^{[1
]}

FaussonePellegrini, MS ^{[1
]}

机构：

[1] UNIV FLORENCE,DEPT HUMAN ANAT & HISTOL,SECT HISTOL E ALLARA,I-50139 FLORENCE,ITALY

来源：

NEUROSCIENCE LETTERS | 1997年 / 229卷 / 01期

关键词：

electron microscope; enteric nervous system; histochemistry; interstitial cells of Cajal; ileum; nitric oxide; nitric oxide synthase; rat;

D O I：

10.1016/S0304-3940(97)00414-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The location of neuronal nitric oxide synthase-immunoreactivity (NOS-IR) in whole mount preparations of muscularis externa of rat ileum was determined by using pre-embedding electron microscope immunocytochemistry. Several neurons, nerve fibers and nerve endings in the myenteric plexus (MP) and nerve endings within the muscle layers were found to be NOS-IR. These nerve endings were especially numerous in the deep muscular plexus (DMP) and much closer to interstitial cells of Cajal (ICC) than to smooth muscle cells, Some of the ICC-MP were NOS-IR. These findings indicate that ICC-MP are apparently able to produce NO and ICC-DMP are the ileal ICC type very richly innervated by the NO releasing nerves. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：45 / 48

页数：4

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