Green protocol: catalyst-free synthesis of 2-substituted benzimidazoles under ultrasound irradiation

被引：3
作者：
Mentese, Emre
Kahveci, Bahittin
Mentese, Meltem
机构：
[1] Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdogan University, Rize
[2] Department of Nutrition and Dietetics, Faculty of Health Sciences, Karadeniz Technical University, Trabzon
来源：
JOURNAL OF CHEMICAL RESEARCH | 2018年 / 06期
关键词：
o-phenylenediamine; imino ester hydrochloride; benzimidazole; ultrasonic irradiation; MICROWAVE-ASSISTED SYNTHESIS; VITRO ANTIMICROBIAL ACTIVITY; EFFICIENT SYNTHESIS; MOLECULAR DOCKING; DERIVATIVES; INHIBITORS;
D O I：
10.3184/174751918X15293267526838
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of 2-substituted benzimidazoles from the reaction of o-phenylenediamine and an imino ester hydrochloride with ultrasound irradiation is reported. The procedure has an eco-friendly and simple workup with good yield in a short time.
引用
收藏
页码：329 / 331
页数：3
相关论文
共 30 条
[1]   A novel sodium iodide and ammonium molybdate co-catalytic system for the efficient synthesis of 2-benzimidazoles using hydrogen peroxide under ultrasound irradiation [J].
Bai, Guo-Yi ;
Lan, Xing-Wang ;
Chen, Guo-Feng ;
Liu, Xiao-Fang ;
Li, Tian-Yu ;
Shi, Ling-Juan .
ULTRASONICS SONOCHEMISTRY, 2014, 21 (02) :520-526
[2]   Recent developments on ultrasound-assisted one-pot multicomponent synthesis of biologically relevant heterocycles [J].
Banerjee, Bubun .
ULTRASONICS SONOCHEMISTRY, 2017, 35 :15-35
[3]   Identification of Phenoxyalkylbenzimidazoles with Antitubercular Activity [J].
Chandrasekera, N. Susantha ;
Alling, Torey ;
Bailey, Mai A. ;
Files, Megan ;
Early, Julie V. ;
Ollinger, Juliane ;
Ovechkina, Yulia ;
Masquelin, Thierry ;
Desai, Prashant V. ;
Cramer, Jeffrey W. ;
Hipskind, Philip A. ;
Odingo, Joshua O. ;
Parish, Tanya .
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (18) :7273-7285
[4]   Green route for the heterocyclization of 2-mercaptobenzimidazole into β-lactum segment derivatives containing -CONH- bridge with benzimidazole:: Screening in vitro antimicrobial activity with various microorganisms [J].
Desai, Krunal G. ;
Desai, Kishor R. .
BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (24) :8271-8279
[5]   Convenient ultrasound-mediated synthesis of 1,4-diazabutadienes under solvent-free conditions [J].
He, Jing-Yu ;
Xin, Hong-Xing ;
Yan, Hong ;
Song, Xiu-Qing ;
Zhong, Ru-Gang .
ULTRASONICS SONOCHEMISTRY, 2011, 18 (01) :466-469
[6]   Synthesis of 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their isatin-3-imine derivatives [J].
Kahveci, B .
MOLECULES, 2005, 10 (02) :376-382
[7]  
Kahveci B, 2017, CURR MICROWAV CHEM, V4, P73, DOI 10.2174/2213335603666160517154048
[8]   An efficient synthesis of some new bisbenzimidazoles via microwave technique [J].
Kahveci, Bahittin ;
Karaali, Nesrin ;
Yilmaz, Fatih ;
Mentese, Emre .
TURKISH JOURNAL OF CHEMISTRY, 2014, 38 (03) :423-429
[9]   Synthesis of new perimidine derivatives from the reaction of 1,8-diaminonapthalene with iminoester hydrochlorides [J].
Kahveci, Bahittin ;
Karaali, Nesrin ;
Mentese, Emre ;
Yilmaz, Fatih .
JOURNAL OF CHEMICAL RESEARCH, 2013, (06) :377-379
[10]   An efficient synthesis of benzimidazoles via a microwave technique and evaluation of their biological activities [J].
Kahveci, Bahittin ;
Mentes, Emre ;
Ozil, Musa ;
Ulker, Serdar ;
Erturk, Murat .
MONATSHEFTE FUR CHEMIE, 2013, 144 (07) :993-1001
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