Defining and validating bipolar disorder in the preschool period

被引:40
作者
Luby, Joan [1 ]
Belden, Andy [1 ]
机构
[1] Washington Univ, Dept Psychiat, Sch Med, St Louis, MO 63110 USA
关键词
D O I
10.1017/S0954579406060482
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
The clinical characteristics and adaptive functioning of preschoolers who met DSM-IV criteria for bipolar disorder versus psychiatric and healthy comparison groups were investigated. A community-based sample of 303 preschoolers (3-6 years of age) and their caregivers was ascertained. Diagnostic classification based on parent report of mania symptoms was made using an age-appropriate psychiatric interview. Results indicated that 26 preschoolers met DSM-IV criteria for bipolar disorder who could be identified based the presence of 13 core age-adjusted mania items. These children could be clearly differentiated from children in two psychiatric groups (DSM-IV disruptive disorders, and major depressive disorder) and a "healthy" comparison group based on a specific symptom constellation. Findings indicated that preschoolers in the bipolar group were significantly more (p < .05) impaired than the two psychiatric and healthy groups based on independent measures. Further, even after controlling for comorbid attention-deficit/hyperactivity disorder (81% comorbidity rate), the bipolar group remained significantly (p < .05) more impaired in multiple domains compared to preschoolers with DSM-IV disruptive disorders and healthy controls. Findings suggested that children as young as 3 years can manifest DSM-IV bipolar disorder when age adjusted symptom descriptions are employed, and that these children can be distinguished from healthy and disruptive disordered preschoolers. Recommendations for future research in this area that integrates developmental and mental health models are made.
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页码:971 / 988
页数:18
相关论文
共 72 条
[1]   The Child and Adolescent Psychiatric Assessment (CAPA) [J].
Angold, A ;
Costello, EJ .
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2000, 39 (01) :39-48
[2]   Further evidence of unique developmental phenotypic correlates of pediatric bipolar disorder: findings from a large sample of clinically referred preadolescent children assessed over the last 7 years [J].
Biederman, J ;
Faraone, SV ;
Wozniak, J ;
Mick, E ;
Kwon, A ;
Aleardi, M .
JOURNAL OF AFFECTIVE DISORDERS, 2004, 82 :S45-S58
[3]   DEVELOPMENTAL SUBTYPES OF JUVENILE BIPOLAR DISORDER [J].
BIEDERMAN, J .
HARVARD REVIEW OF PSYCHIATRY, 1995, 3 (04) :227-230
[4]   The naturalistic course of pharmacologic treatment of children with maniclike symptoms: A systematic chart review [J].
Biederman, J ;
Mick, E ;
Bostic, JQ ;
Prince, J ;
Daly, J ;
Wilens, TE ;
Spencer, T ;
Garcia-Jetton, J ;
Russell, R ;
Wozniak, J ;
Faraone, SV .
JOURNAL OF CLINICAL PSYCHIATRY, 1998, 59 (11) :628-637
[5]   Harsh parenting in relation to child emotion regulation and aggression [J].
Chang, L ;
Schwartz, D ;
Dodge, KA ;
McBride-Chang, C .
JOURNAL OF FAMILY PSYCHOLOGY, 2003, 17 (04) :598-606
[6]  
Cicchetti D., 1995, DEV PSYCHOPATHOL, V2, P369
[7]  
CICCHETTI D, 1995, EMOTION COGNITION RE
[8]  
CLARK AF, 2004, CLIN APPROACHES BIPO, V3, P55
[9]  
CLARK AF, 2004, CLIN APPROACHES BIPO, V3, P49
[10]  
Cole P M, 1994, Monogr Soc Res Child Dev, V59, P73