Trends of genetic relationship of serotype 23F penicillin-resistant Streptococcus pneumoniae in Japan

被引：6

作者：

Yoshida, R ^{[1
]}

Hirakata, Y ^{[1
]}

Kaku, M ^{[1
]}

Takemura, H ^{[1
]}

Tanaka, H ^{[1
]}

Tomono, K ^{[1
]}

Koga, H ^{[1
]}

Kohno, S ^{[1
]}

Kamihira, S ^{[1
]}

机构：

[1] NAGASAKI UNIV, SCH MED, DEPT INTERNAL MED 2, NAGASAKI 852, JAPAN

来源：

CHEMOTHERAPY | 1997年 / 43卷 / 04期

关键词：

penicillin-resistant; Streptococcus pneumoniae; pulsed-field gel electrophoresis; ceftriaxone resistant; erythromycin resistant; tetracycline resistant;

D O I：

10.1159/000239572

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

No data on the genetic analysis of penicillin-resistant Streptococcus pneumoniae (PRP) in Japan has been reported. The SmaI restriction endonuclease digested patterns of chromosomal DNAs from 15 PRP serotyped 23F isolated in Japan were analyzed by pulsed-field gel electrophoresis (PFGE). The isolates were genetically heterogeneous and seven different PFGE patterns were identified. Nine strains were also resistant to erythromycin and tetracycline. Four strains revealed resistance to ceftriaxone. The PFGE patterns of some strains isolated in Nagasaki University Hospital were identical to each other and closely resembled those of isolates from three different areas of Japan. These results indicate a need for additional studies by PFGE to determine the possibility of clonal spread in Japan.

引用

页码：232 / 238

页数：7

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