TMEDA Catalyzed Henry (Nitroaldol) Reaction under Metal and Solvent-free Conditions

被引：1

作者：

Majhi, Anjoy ^{[1
]}

Kadam, Santosh T. ^{[1
]}

Kim, Sung Soo ^{[1
]}

机构：

[1] Inha Univ, Dept Chem, Inchon 402751, South Korea

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2009年 / 30卷 / 08期

关键词：

TMEDA; Nitroaldol; Solvent-free; beta-Nitro alkanol; ALPHA-AMINO ALDEHYDES; EFFICIENT SILYLCYANATION; STEREOSPECIFIC SYNTHESIS; CYANOSILYLATION; MILD; ALCOHOLS; ACID; VINYLALUMINATION;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Henry (nitroaldol) reaction proceeds under mild conditions with catalytic amount of tetramethylethylenediamine (TMEDA) to afford beta-nitro alkanol in considerably excellent yield. Structurally diverse aldehydes react with nitromethane in presence of 0.3 equiv of TMEDA Under solvent-free condition at rt. The low catalytic loading and mild reaction condition are the key features of the catalytic method.

引用

页码：1767 / 1770

页数：4

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