Asymmetric cyclopropanation of olefins with diazoacetate using chiral copper catalysts

被引：37

作者：

Ichiyanagi, T ^{[1
]}

Shimizu, M ^{[1
]}

Fujisawa, T ^{[1
]}

机构：

[1] MIE UNIV, DEPT CHEM MAT, TSU, MIE 514, JAPAN

来源：

TETRAHEDRON | 1997年 / 53卷 / 28期

关键词：

D O I：

10.1016/S0040-4020(97)00644-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral 2-(2-aryl- or 2-alkyl-sufonylamino)phenyl-4-phenyl-1,3-oxazolines were found to be effective ligands for copper-catalyzed enantioselective cyclopropanation reaction of olefins. The reaction of styrene with d-menthyl diazoacetate in the presence of optically active copper catalysts gave cyclopropanation products in a ratio of irans: cis = 83 : 17 with 63% ee (trans) and 84% ee (cis). (C) 1997 Elsevier Science Ltd.

引用

页码：9599 / 9610

页数：12

共 38 条

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