Dasatinib and allogeneic stem cell transplantation enable sustained response in an elderly patient with RCSD1-ABL1-positive acute lymphoblastic leukemia

被引：15
作者：
Frech, Miriam [1 ,2 ]
Jehn, Lutz B. [1 ,2 ]
Stabla, Kathleen [1 ,2 ]
Mielke, Stephan [3 ]
Steffen, Bjoern [4 ]
Einsele, Hermann [3 ]
Metzelder, Stephan K. [1 ,2 ]
Neubauer, Andreas [1 ,2 ]
机构：
[1] Philipps Univ Marburg, Dept Internal Med & Hematol Oncol & Immunol, Baldingerstr, Marburg, Germany
[2] Univ Hosp Giessen & Marburg, Baldingerstr, Marburg, Germany
[3] Univ Hosp Wurzburg, Dept Internal Med 2, Oberdurrbacher Str 6, Wurzburg, Germany
[4] Goethe Univ Frankfurt, Dept Med, Hematol Oncol, Theodor Stern Kai 7, Frankfurt, Germany
来源：
HAEMATOLOGICA | 2017年 / 102卷 / 04期
关键词：
TYROSINE-KINASE INHIBITORS; GENE; T(1/9)(Q24; Q34); FUSION; ABL1;
D O I：
10.3324/haematol.2016.160531
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：E160 / E162
页数：3
相关论文
共 15 条
  • [1] Drug response profiling can predict response to ponatinib in a patient with t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia
    Collette, Y.
    Prebet, T.
    Goubard, A.
    Adelaide, J.
    Castellano, R.
    Carbuccia, N.
    Garnier, S.
    Guille, A.
    Arnoulet, C.
    Charbonier, A.
    Mozziconacci, M. J.
    Birnbaum, D.
    Chaffanet, M.
    Vey, N.
    [J]. BLOOD CANCER JOURNAL, 2015, 5 : e292 - e292
  • [2] A new partner gene fused to ABL1 in a t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia
    De Braekeleer, E.
    Douet-Guilbert, N.
    Le Bris, M-J
    Berthou, C.
    Morel, F.
    De Braekeleer, M.
    [J]. LEUKEMIA, 2007, 21 (10) : 2220 - 2221
  • [3] Acute lymphoblastic leukemia associated with RCSD1-ABL1 novel fusion gene has a distinct gene expression profile from BCR-ABL1 fusion
    De Braekeleer, E.
    Douet-Guilbert, N.
    Guardiola, P.
    Rowe, D.
    Mustjoki, S.
    Zamecnikova, A.
    Al Bahar, S.
    Jaramillo, G.
    Berthou, C.
    Bown, N.
    Porkka, K.
    Ochoa, C.
    De Braekeleer, M.
    [J]. LEUKEMIA, 2013, 27 (06) : 1422 - 1424
  • [4] ABL1 fusion genes in hematological malignancies: a review
    De Braekeleer, Etienne
    Douet-Guilbert, Nathalie
    Rowe, David
    Bown, Nick
    Morel, Frederic
    Berthou, Christian
    Ferec, Claude
    De Braekeleer, Marc
    [J]. EUROPEAN JOURNAL OF HAEMATOLOGY, 2011, 86 (05) : 361 - 371
  • [5] The t(1;9)(p34;q34) fusing ABL1 with SFPQ, a pre-mRNA processing gene, is recurrent in acute lymphoblastic leukemias
    Duhoux, Francois P.
    Auger, Nathalie
    De Wilde, Sigrid
    Wittnebel, Sebastian
    Ameye, Genevieve
    Bahloula, Khadija
    Van den Berg, Catherine
    Libouton, Jeanne-Marie
    Saussoy, Pascale
    Grand, Francis H.
    Demoulin, Jean-Baptiste
    Poirel, Helene A.
    [J]. LEUKEMIA RESEARCH, 2011, 35 (07) : E114 - E117
  • [6] The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ
    Eyers, CE
    McNeill, H
    Knebel, A
    Morrice, N
    Arthur, SJC
    Cuenda, A
    Cohen, P
    [J]. BIOCHEMICAL JOURNAL, 2005, 389 : 127 - 135
  • [7] RCSD1-ABL1-positive B lymphoblastic leukemia is sensitive to dexamethasone and tyrosine kinase inhibitors and rapidly evolves clonally by chromosomal translocations
    Inokuchi, Koiti
    Wakita, Satoshi
    Hirakawa, Tsuneaki
    Tamai, Hayato
    Yokose, Norio
    Yamaguchi, Hiroki
    Dan, Kazuo
    [J]. INTERNATIONAL JOURNAL OF HEMATOLOGY, 2011, 94 (03) : 255 - 260
  • [8] GRAFT-VERSUS-LEUKEMIA EFFECT OF DONOR LYMPHOCYTE TRANSFUSIONS IN MARROW GRAFTED PATIENTS
    KOLB, HJ
    SCHATTENBERG, A
    GOLDMAN, JM
    HERTENSTEIN, B
    JACOBSEN, N
    ARCESE, W
    LJUNGMAN, P
    FERRANT, A
    VERDONCK, L
    NIEDERWIESER, D
    VANRHEE, F
    MITTERMUELLER, J
    DEWITTE, T
    HOLLER, E
    ANSARI, H
    [J]. BLOOD, 1995, 86 (05) : 2041 - 2050
  • [9] A novel dasatinib-sensitive RCSD1-ABL1 fusion transcript in chemotherapy-refractory adult pre-B lymphoblastic leukemia with t(1;9)(q24;q34)
    Mustjoki, Satu
    Hernesmenn, Sari
    Ranhala, Anvo
    Kahkonen, Marketta
    Almqvist, Anders
    Lundan, Tuija
    Porkka, Kimmo
    [J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 (10): : 1469 - 1471
  • [10] Ottmann O G, 2012, Leuk Suppl, V1, pS7, DOI 10.1038/leusup.2012.7
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