Methods for the classification of leprosy for treatment purposes

被引：74

作者：

Pardillo, Fe Eleanor F.

Fajardo, Tranquilino T.

Abalos, Rodolfo M.

Scollard, David

Gelber, Robert H.

机构：

[1] Leonard Wood Mem Ctr Leprosy Res, Cebu, Philippines

[2] Gillis W Long Hansens Dis Ctr, Baton Rouge, LA USA

来源：

CLINICAL INFECTIOUS DISEASES | 2007年 / 44卷 / 08期

关键词：

D O I：

10.1086/512809

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The World Health Organization advocates 2 leprosy treatment regimens on the basis of disease classification (as multibacillary or paucibacillary) by skin lesion count. This method, which, in the Philippines, results in a high prevalence (78%) of patients with multibacillary leprosy, was directly compared with classification using standard histopathological and microbiological criteria in 264 currently untreated patients with leprosy. Of those whose leprosy was classified as paucibacillary, 38%-51% of patients had multibacillary leprosy according to classic criteria and were thus at risk of undertreatment according to World Health Organization recommendations.

引用

页码：1096 / 1099

页数：4