Maternal Immunization

被引：28
作者：
Chu, Helen Y. [1 ]
Englund, Janet A. [1 ,2 ]
机构：
[1] Univ Washington, Dept Med, Div Allergy & Infect Dis, Seattle, WA USA
[2] Univ Washington, Dept Infect Dis, Seattle Childrens Hosp, Seattle, WA 98195 USA
来源：
BIRTH DEFECTS RESEARCH | 2017年 / 109卷 / 05期
关键词：
maternal immunization; influenza; tetanus; diphtheria; pertussis; INFLUENZAE TYPE-B; PNEUMOCOCCAL POLYSACCHARIDE VACCINE; SYNCYTIAL VIRUS-INFECTION; PROTEIN CONJUGATE VACCINE; PREGNANT-WOMEN; ANTIBODY TRANSFER; ADVISORY-COMMITTEE; PLACENTAL-TRANSFER; PERTUSSIS-VACCINE; HIV-INFECTION;
D O I：
10.1002/bdra.23547
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Pregnant women, neonates, and infants are at higher risk for severe infections due to vaccine-preventable diseases. Very young infants rarely respond well to vaccination due to poor immunogenicity and interference from maternal antibody. Maternal immunization protects the mother and fetus from disease and protects the infant through transplacental antibody transfer through the first 6 months of life. Currently, immunizations routinely recommended during pregnancy include inactivated influenza, tetanus toxoid, and acellular pertussis vaccines. Promising maternal vaccine candidates in development include a group B streptococcus vaccine and a respiratory syncytial virus vaccine. (C) 2017 Wiley Periodicals, Inc.
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收藏
页码：379 / 386
页数：8
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