Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

被引：8
作者：
Weng, Qinjie [1 ]
Li, Xiao [1 ]
Ren, Hong [1 ]
Xie, Jingyuan [1 ]
Pan, Xiaoxia [1 ]
Xu, Jing [1 ]
Chen, Nan [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Dept Nephrol, Shanghai 200030, Peoples R China
来源：
ONCOTARGET | 2017年 / 8卷 / 13期
关键词：
hepatitis C virus; membranous nephropathy; hepatitis C virus-related glomerulonephritis; Ledipasvir-Sofosbuvir; case report; GENOTYPE; 1; INFECTION; KIDNEY-DISEASE; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; RENAL-DISEASE; HCV; THERAPY; JAPAN; PLUS;
D O I：
10.18632/oncotarget.15397
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various. Case summary: We report a case of patient with chronic HCV infection and MN, who presented with was proteinuria. He was treated with ledipasvir and sofosbuvir (Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free. Conclusion: We have reported this case to provide insight into whether Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis.
引用
收藏
页码：22299 / 22303
页数：5
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