Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

被引:8
|
作者
Weng, Qinjie [1 ]
Li, Xiao [1 ]
Ren, Hong [1 ]
Xie, Jingyuan [1 ]
Pan, Xiaoxia [1 ]
Xu, Jing [1 ]
Chen, Nan [1 ]
机构
[1] Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Dept Nephrol, Shanghai 200030, Peoples R China
关键词
hepatitis C virus; membranous nephropathy; hepatitis C virus-related glomerulonephritis; Ledipasvir-Sofosbuvir; case report; GENOTYPE; 1; INFECTION; KIDNEY-DISEASE; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; RENAL-DISEASE; HCV; THERAPY; JAPAN; PLUS;
D O I
10.18632/oncotarget.15397
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various. Case summary: We report a case of patient with chronic HCV infection and MN, who presented with was proteinuria. He was treated with ledipasvir and sofosbuvir (Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free. Conclusion: We have reported this case to provide insight into whether Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis.
引用
收藏
页码:22299 / 22303
页数:5
相关论文
共 50 条
  • [1] Effectiveness of Ledipasvir-Sofosbuvir Combination in Patients With Hepatitis C Virus Infection and Factors Associated With Sustained Virologic Response
    Terrault, Norah A.
    Zeuzem, Stefan
    Di Bisceglie, Adrian M.
    Lim, Joseph K.
    Pockros, Paul J.
    Frazier, Lynn M.
    Kuo, Alexander
    Lok, Anna S.
    Shiffman, Mitchell L.
    Ben Ari, Ziv
    Akushevich, Lucy
    Vainorius, Monika
    Sulkowski, Mark S.
    Fried, Michael W.
    Nelson, David R.
    GASTROENTEROLOGY, 2016, 151 (06) : 1131 - +
  • [2] Risk of Hepatitis B Virus Reactivation Among Patients Treated With Ledipasvir-Sofosbuvir for Hepatitis C Virus Infection
    Yanny, Beshoy T.
    Latt, Nyan L.
    Saab, Sammy
    Han, Steven
    Choi, Gina
    Kramer, Jason
    Sahota, Amandeep K.
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 2018, 52 (10) : 908 - 912
  • [3] Ledipasvir-sofosbuvir for hepatitis C genotype 4 infection
    Smith, Michael A.
    Mohammad, Rima A.
    LANCET INFECTIOUS DISEASES, 2015, 15 (09): : 993 - 995
  • [4] Generic Ledipasvir-Sofosbuvir Treatment for Adolescents With Chronic Hepatitis C Virus Infection
    Fouad, Hanan M.
    Sabry, Magda A.
    Ahmed, Amal
    Hassany, Mohamed
    Al Soda, Mohamed F.
    Aziz, Hossam Abdel
    JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 2020, 9 (03) : 386 - 389
  • [5] Treatment of Patients With Hepatitis C Virus Infection With Ledipasvir-Sofosbuvir in the Liver Transplant Setting
    Abaalkhail, Faisal
    Elsiesy, Hussein
    Elbeshbeshy, Hany
    Shawkat, Mohamed
    Yousif, Sarra
    Ullah, Waheed
    Alabbad, Saleh
    Al-jedai, Ahmed
    Ajlan, Aziza
    Broering, Dieter
    Saab, Sammy
    Al Sebayel, Mohammed
    Al-Hamoudi, Waleed
    TRANSPLANTATION, 2017, 101 (11) : 2739 - 2745
  • [6] Safety and Efficacy of Ledipasvir-Sofosbuvir in Black Patients With Hepatitis C Virus Infection: A Retrospective Analysis of Phase 3 Data
    Wilder, Julius M.
    Jeffers, Lennox J.
    Ravendhran, Natarajan
    Shiffman, Mitchell L.
    Poulos, John
    Sulkowski, Mark S.
    Gitlin, Norman
    Workowski, Kimberly
    Zhu, Yanni
    Yang, Jenny C.
    Pang, Phillip S.
    McHutchison, John G.
    Muir, Andrew J.
    Howell, Charles
    Kowdley, Kris
    Afdhal, Nezam
    Reddy, K. Rajender
    HEPATOLOGY, 2016, 63 (02) : 437 - 444
  • [7] Ledipasvir-Sofosbuvir: Interferon-/ Ribavirin-Free Regimen for Chronic Hepatitis C Virus Infection
    Smith, Michael A.
    Chan, Juliana
    Mohammad, Rima A.
    ANNALS OF PHARMACOTHERAPY, 2015, 49 (03) : 343 - 350
  • [8] Ledipasvir-sofosbuvir for treating Japanese patients with chronic hepatitis C virus genotype 2 infection
    Asahina, Yasuhiro
    Itoh, Yoshito
    Ueno, Yoshiyuki
    Matsuzaki, Yasushi
    Takikawa, Yasuhiro
    Yatsuhashi, Hiroshi
    Genda, Takuya
    Ikeda, Fusao
    Matsuda, Takuma
    Dvory-Sobol, Hadas
    Jiang, Deyuan
    Massetto, Benedetta
    Osinusi, Anu O.
    Brainard, Diana M.
    McHutchison, John G.
    Kawada, Norifumi
    Enomoto, Nobuyuki
    LIVER INTERNATIONAL, 2018, 38 (09) : 1552 - 1561
  • [9] Ledipasvir-sofosbuvir plus ribavirin for patients with genotype 1 hepatitis C virus previously treated in clinical trials of sofosbuvir regimens
    Wyles, David
    Pockros, Paul
    Morelli, Giuseppe
    Younes, Ziad
    Svarovskaia, Evguenia
    Yang, Jenny C.
    Pang, Phillip S.
    Zhu, Yanni
    McHutchison, John G.
    Flamm, Steven
    Lawitz, Eric
    HEPATOLOGY, 2015, 61 (06) : 1793 - 1797
  • [10] Treatment of chronic hepatitis C virus infection in Rwanda with ledipasvir-sofosbuvir (SHARED): a single-arm trial
    Gupta, Neil
    Mbituyumuremyi, Aimable
    Kabahizi, Jules
    Ntaganda, Fabien
    Muvunyi, Claude Mambo
    Shumbusho, Fabienne
    Musabeyezu, Emmanuel
    Mukabatsinda, Constance
    Ntirenganya, Cyprien
    Van Nuil, Jennifer Ilo
    Kateera, Fredrick
    Camus, Gregory
    Damascene, Makuza Jean
    Nsanzimana, Sabin
    Mukherjee, Joia
    Grant, Philip M.
    LANCET GASTROENTEROLOGY & HEPATOLOGY, 2019, 4 (02): : 119 - 126