Chemical measurements in Drosophila

被引：8

作者：

Makos, Monique A. ^{[1
]}

Kuklinski, Nicholas J. ^{[1
,2
]}

Berglund, E. Carina ^{[2
]}

Heien, Michael L. ^{[1
]}

Ewing, Andrew G. ^{[1
,2
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

[2] Univ Gothenburg, Dept Chem, SE-41296 Gothenburg, Sweden

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2009年 / 28卷 / 11期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

Capillary electrophoresis; Embryo; Drosophila; High-performance liquid chromatography; in vivo electrochemistry; Larvae; Mass spectrometry; MEMS-based system; Micellar electrokinetic chromatography; Microfluidics; CENTRAL-NERVOUS-SYSTEM; MUSHROOM BODY NEURONS; BIOGENIC-AMINES; IN-VIVO; PROTEIN EXPRESSION; ALPHA-SYNUCLEIN; WILD-TYPE; MELANOGASTER; DOPAMINE; MODEL;

D O I：

10.1016/j.trac.2009.08.005

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry, and technologies involving intact organisms, including in vivo electrochemistry. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1223 / 1234

页数：12

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