Phosphorylated PmrA interacts with the promoter region of ugd in Salmonella enterica serovar Typhimurium

被引:43
作者
Aguirre, A [1 ]
Lejona, S [1 ]
Véscovi, EG [1 ]
Soncini, FC [1 ]
机构
[1] Univ Nacl Rosario, Dept Microbiol, Fac Ciencias Bioquim & Farmaceut, RA-2000 Rosario, Santa Fe, Argentina
关键词
D O I
10.1128/JB.182.13.3874-3876.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Salmonella PmrA-PmrB system controls the expression of genes necessary for polymyxin B resistance. Four loci were previously identified as part of the regulon, and interaction of PmrA with the promoter region of three of them was observed. Here we characterized the interaction of PmrA with the promoter region of ugd, previously suggested to be regulated indirectly by PmrA. Our results indicate that PmrA controls the expression of ugd by interacting with a specific sequence in the promoter region of this gene.
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页码:3874 / 3876
页数:3
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