Clinical and microbiological effects of an essential-oil-containing mouth rinse applied in the "one-stage full-mouth disinfection" protocol-a randomized doubled-blinded preliminary study

被引:18
作者
Cortelli, Sheila Cavalca [1 ]
Cavallini, Fabiana [2 ]
Regueira Alves, Marcello Faria [2 ]
Bezerra, Arnaud Alves, Jr. [2 ]
Queiroz, Celso Silva [3 ]
Cortelli, Jose Roberto [1 ]
机构
[1] Univ Taubate, Dent Res Div, Dept Periodontol & Prevent Dent, BR-12010700 Sao Paulo, Brazil
[2] Univ Taubate, Dent Res Div, Dept Periodontol, BR-12010700 Sao Paulo, Brazil
[3] Univ Taubate, Dent Res Div, Dept Oral Biol, BR-12010700 Sao Paulo, Brazil
关键词
Essential oils; Clinical trials; Periodontitis; Therapy; Full-mouth disinfection; NONSURGICAL PERIODONTAL THERAPY; EARLY-ONSET PERIODONTITIS; CHRONIC ADULT; CHLORHEXIDINE; MAINTENANCE; INFECTIONS; PLAQUE;
D O I
10.1007/s00784-008-0219-3
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The aim of this randomized double-blinded preliminary study was to evaluate the clinical and microbiological long-term effects of an essential-oil-containing mouth rinse as the active agent utilized in the "one-stage full-mouth disinfection protocol." Probing pocket depth and plaque and gingival indices were evaluated by the same calibrated examiner in all teeth of 20 moderate chronic periodontitis subjects. Presence of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and Tannerella forsythensis were determined by polymerase chain reaction in nonstimulated saliva, tongue dorsum, and pooled subgingival samples. The subjects were randomized into two groups: full-mouth disinfection plus essential oils (Listerine) or full-mouth disinfection plus placebo. Clinical and microbial parameters were evaluated at baseline (TO), 45 (T1) and 180 (T2) days after therapy and analyzed using analysis of variance, Student t, and Wilcoxon tests (p<0.05). No significant ferences were observed between groups regarding clinical measurements at baseline. However, in the later examinations, T 1 and T2, the test group always presented higher reductions of pocket depth, plaque index, and gingival index compared to the control group. The essential-oils group revealed significant reduction on occurrence of P. gingivalis in saliva comparing baseline and 45 days; this difference still remain at 180 days. The essential-oil-containing mouth rinse demonstrated beneficial effects on clinical parameters. Microbiological findings were less consistent. The results of this preliminary study suggest further investigations.
引用
收藏
页码:189 / 194
页数:6
相关论文
共 36 条
[1]   Reproducibility of probing depth measurements using a constant-force electronic probe: Analysis of inter- and intraexaminer variability [J].
Araujo, MWB ;
Hovey, KM ;
Benedek, JR ;
Grossi, SG ;
Dorn, J ;
Wactawski-Wende, J ;
Genco, RJ ;
Trevisan, M .
JOURNAL OF PERIODONTOLOGY, 2003, 74 (12) :1736-1740
[2]   THE ROLE OF DENTAL PROFESSIONALS AND THE PATIENT IN PLAQUE CONTROL [J].
BAKER, KA .
PERIODONTOLOGY 2000, 1995, 8 :108-113
[3]   Full- versus partial-mouth disinfection in the treatment of periodontal infections - A pilot study: Long-term microbiological observations [J].
Bollen, CML ;
Vandekerckhove, BNA ;
Papaioannou, W ;
VanEldere, J ;
Quirynen, M .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1996, 23 (10) :960-970
[4]   The effect of a one-stage full-mouth disinfection on different intra-oral niches - Clinical and microbiological observations [J].
Bollen, CML ;
Mongardini, C ;
Papaioannou, W ;
Van Steenberghe, D ;
Quirynen, M .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1998, 25 (01) :56-66
[5]   Comparative antiplaque and antigingivitis effectiveness of a chlorhexidine and an essential oil mouthrinse: 6-month clinical trial [J].
Charles, CH ;
Mostler, KM ;
Bartels, LL ;
Mankodi, SM .
JOURNAL OF CLINICAL PERIODONTOLOGY, 2004, 31 (10) :878-884
[6]  
Ciancio S G, 2000, Compend Contin Educ Dent, V21, P59
[7]   THE EFFECT OF AN ANTISEPTIC MOUTHRINSE ON IMPLANT MAINTENANCE - PLAQUE AND PERI-IMPLANT GINGIVAL TISSUES [J].
CIANCIO, SG ;
LAUCIELLO, F ;
SHIBLY, O ;
VITELLO, M ;
MATHER, M .
JOURNAL OF PERIODONTOLOGY, 1995, 66 (11) :962-965
[8]   Prevalence of periodontal pathogens in Brazilians with aggressive or chronic periodontitis [J].
Cortelli, JR ;
Cortelli, SC ;
Jordan, S ;
Haraszthy, VI ;
Zambon, JJ .
JOURNAL OF CLINICAL PERIODONTOLOGY, 2005, 32 (08) :860-866
[9]   Detection of Actinobacillus actinomycetemcomitans in unstimulated saliva of patients with chronic periodontitis [J].
Cortelli, SC ;
Feres, M ;
Rodrigues, AAB ;
Aquino, DR ;
Shibli, JA ;
Cortelli, JR .
JOURNAL OF PERIODONTOLOGY, 2005, 76 (02) :204-209
[10]  
Ernst CP, 2005, QUINTESSENCE INT, V36, P641