Immune complex formation in IgA nephropathy: a case of the 'right' antibodies in the 'wrong' place at the 'wrong' time?

被引:37
作者
Barratt, Jonathan [1 ,2 ]
Eitner, Frank [3 ]
Feehally, John [1 ]
Floege, Juergen [2 ,3 ]
机构
[1] Univ Leicester, Dept Infect Immun & Inflammat, Leicester, Leics, England
[2] Univ Hosp Leicester NHS Trust, John Walls Renal Unit, Leicester, Leics, England
[3] RWTH Univ Hosp Aachen, Dept Nephrol & Clin Immunol, Aachen, Germany
关键词
immune complex; molecular mimicry; mucosal immunity; O-glycosylation; ABERRANT O-GLYCOSYLATION; CHAIN MESSENGER-RNA; MASS-SPECTROMETRY; EXPRESSION; CELLS; PATHOGENESIS; MUCOSAL; SYSTEM;
D O I
10.1093/ndt/gfp441
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
引用
收藏
页码:3620 / 3623
页数:5
相关论文
共 20 条
[1]   Mesangial IgA1 in IgA nephropathy exhibits aberrant O-glycosylation: Observations in three patients [J].
Allen, AC ;
Bailey, EM ;
Brenchley, PEC ;
Buck, KS ;
Barratt, J ;
Feehally, J .
KIDNEY INTERNATIONAL, 2001, 60 (03) :969-973
[2]  
ALLEN AC, 1995, CLIN EXP IMMUNOL, V100, P470
[3]   Exaggerated systemic antibody response to mucosal Helicobacter pylori infection in IgA nephropathy [J].
Barratt, J ;
Bailey, EM ;
Buck, KS ;
Mailley, J ;
Moayyedi, P ;
Feehally, J ;
Turney, JH ;
Crabtree, JE ;
Allen, AC .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1999, 33 (06) :1049-1057
[4]   Immunopathogenesis of IgAN [J].
Barratt, Jonathan ;
Smith, Alice C. ;
Molyneux, Karen ;
Feehally, John .
SEMINARS IN IMMUNOPATHOLOGY, 2007, 29 (04) :427-443
[5]   T-cell homing receptor expression in IgA nephropathy [J].
Batra, Arvind ;
Smith, Alice C. ;
Feehally, John ;
Barratt, Jonathan .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2007, 22 (09) :2540-2548
[6]   Altered expression of lymphocyte homing chemokines in the pathogenesis of IgA nephropathy [J].
Buren, Marc ;
Yamashita, Michifumi ;
Suzuki, Yusuke ;
Tomino, Yasuhiko ;
Emancipator, Steven N. .
IGA NEPHROPATHY TODAY, 2007, 157 :50-55
[7]  
COPPO R, 1993, CONTRIB NEPHROL, V104, P162
[8]   SEQUENTIAL STUDY OF THE IGA SYSTEM IN RELAPSING IGA NEPHROPATHY [J].
FEEHALLY, J ;
BEATTIE, TJ ;
BRENCHLEY, PEC ;
COUPES, BM ;
MALLICK, NP ;
POSTLETHWAITE, RJ .
KIDNEY INTERNATIONAL, 1986, 30 (06) :924-931
[9]   Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy [J].
Gharavi, Ali G. ;
Moldoveanu, Zina ;
Wyatt, Robert J. ;
Barker, Catherine V. ;
Woodford, Susan Y. ;
Lifton, Richard P. ;
Mestecky, Jiri ;
Novak, Jan ;
Julian, Bruce A. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2008, 19 (05) :1008-1014
[10]  
HARPER SJ, 1995, CLIN EXP IMMUNOL, V101, P442