Direct One-Pot Reductive Amination of Aldehydes with Nitroarenes in a Domino Fashion: Catalysis by Gum-Acacia-Stabilized Palladium Nanoparticles

被引：139

作者：

Sreedhar, B. ^{[1
]}

Reddy, P. Surendra ^{[1
]}

Devi, D. Keerthi ^{[1
]}

机构：

[1] CSIR, Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 22期

关键词：

CARBONYL-COMPOUNDS; ORGANIC-SYNTHESIS; N-ALKYLATION; KETONES; CYANOBOROHYDRIDE; MONOALKYLATION; HYDROGENATION; CONSTRUCTION; SOLVENT;

D O I：

10.1021/jo901787t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This note describes the direct reductive amination of carbonyl compounds with nitroarenes using gum acacia-palladium nanoparticles, employing molecular hydrogen as the reductant. This methodology is found to be applicable to both aliphatic and aromatic aldehydes and a wide range of nitroarenes. The operational simplicity and the mild reaction conditions add to the value of this method as a practical alternative to the reductive amination of carbonyl compounds.

引用

页码：8806 / 8809

页数：4

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