Sol-gel synthesis of Na2CaSiO4 and its in vitro biological behaviors

被引：32

作者：

Zhao, Yingke ^{[1
]}

Ning, Congqin ^{[1
]}

Chang, Jiang ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China

来源：

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY | 2009年 / 52卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Sodium calcium silicate; Sol-gel; Apatite formation; Biodegradation; BIOACTIVITY; AKERMANITE; CERAMICS;

D O I：

10.1007/s10971-009-2006-2

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Inspired from the success of silicate-based bioactive glasses and glass-ceramics, alkali or/and alkali earth-containing silicate ceramics have attracted much attention in recent years. In the present paper, pure Na2CaSiO4 was successfully synthesized by a sol-gel method and its in vitro biological behaviors were investigated. The results showed that Na2CaSiO4 could quickly induce bone-like apatite formation in simulated body fluid through a silicon-rich layer. The degradation of Na2CaSiO4 in phosphorus buffered saline (PBS) was controlled by two processes: dissolution and back precipitation. Na2CaSiO4 even had the ability to induce apatite formation in PBS, which further confirmed its high apatite-inducing ability.

引用

页码：69 / 74

页数：6

共 15 条

[1] Silicate biomaterials for orthopaedic and dental implants [J].