The SPRINT study: Outcome may be driven by difference in diuretic treatment demasking heart failure and study design may support systolic blood pressure target below 140 mmHg rather than below 120 mmHg

被引:30
作者
Kjeldsen, Sverre E. [1 ]
Narkiewicz, Krzysztof [2 ]
Hedner, Thomas [3 ]
Mancia, Giuseppe [4 ]
机构
[1] Univ Oslo, Ullevaal Hosp, Dept Cardiol, N-0407 Oslo, Norway
[2] Med Univ Gdansk, Dept Hypertens & Diabetol, Gdansk, Poland
[3] Univ Goteborg, Sahlgrenska Acad, Dept Med, Gothenburg, Sweden
[4] Univ Milano Bicocca, Ist Auxol Italiano, IRCCS, Milan, Italy
关键词
OPTIMAL TREATMENT HOT; HYPERTENSION; STROKE;
D O I
10.3109/08037051.2015.1130775
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
引用
收藏
页码:63 / 66
页数:4
相关论文
共 19 条
[1]   The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The Systolic Blood Pressure Intervention Trial (SPRINT) [J].
Ambrosius, Walter T. ;
Sink, Kaycee M. ;
Foy, Capri G. ;
Berlowitz, Dan R. ;
Cheung, Alfred K. ;
Cushman, William C. ;
Fine, Lawrence J. ;
Goff, David C., Jr. ;
Johnson, Karen C. ;
Killeen, Anthony A. ;
Lewis, Cora E. ;
Oparil, Suzanne ;
Reboussin, David M. ;
Rocco, Michael V. ;
Snyder, Joni K. ;
Williamson, Jeff D. ;
Wright, Jackson T., Jr. ;
Whelton, Paul K. .
CLINICAL TRIALS, 2014, 11 (05) :532-546
[2]   Blood-pressure targets in patients with recent lacunar stroke: the SPS3 randomised trial [J].
Benavente, O. R. ;
Coffey, C. S. ;
Conwit, R. ;
Hart, R. G. ;
McClure, L. A. ;
Pearce, L. A. ;
Pergola, P. E. ;
Szychowski, J. M. ;
Benavente, O. R. ;
Hart, R. G. ;
Pergola, P. E. ;
Palacio, S. ;
Castro, I. ;
Farias, A. ;
Roldan, A. ;
Kase, C. ;
Gavras, I. ;
Lau, H. ;
Ogrodnik, M. ;
Allen, N. ;
Meissner, I. ;
Graves, J. ;
Herzig, D. ;
Covalt, J. ;
Meyer, B. ;
Jackson, C. ;
Gamble, P. ;
Kelly, N. ;
Warner, J. ;
Bell, J. ;
Demaerschalk, B. ;
Hogan, M. ;
Wochos, D. ;
Wieser, J. ;
Cleary, B. ;
Wood, L. ;
Hanna, J. ;
Zipp, T. ;
Bailey, S. ;
Cook, D. ;
Liskay, A. ;
Simcox, D. ;
Kappler, J. ;
Anderson, D. ;
Grimm, R. ;
Brauer, D. ;
Pettigrew, C. ;
Vaishnov, A. ;
Sawaya, P. ;
Fowler, A. .
LANCET, 2013, 382 (9891) :507-515
[3]   SPRINT Trial Results Latest News in Hypertension Management [J].
Cushman, William C. ;
Whelton, Paul K. ;
Fine, Lawrence J. ;
Wright, Jackson T. ;
Reboussin, David M. ;
Johnson, Karen C. ;
Oparil, Suzanne .
HYPERTENSION, 2016, 67 (02) :263-265
[4]   Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus [J].
Cushman, William C. ;
Evans, Gregory W. ;
Byington, Robert P. ;
Goff, David C., Jr. ;
Grimm, Richard H., Jr. ;
Cutler, Jeffrey A. ;
Simons-Morton, Denise G. ;
Basile, Jan N. ;
Corson, Marshall A. ;
Probstfield, Jeffrey L. ;
Katz, Lois ;
Peterson, Kevin A. ;
Friedewald, William T. ;
Buse, John B. ;
Bigger, J. Thomas ;
Gerstein, Hertzel C. ;
Ismail-Beigi, Faramarz .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (17) :1575-1585
[5]   SPRINT, or False Start, Toward a Lower Universal Treated Blood Pressure Target in Hypertension [J].
Esler, Murray .
HYPERTENSION, 2016, 67 (02) :266-267
[6]   Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension:: principal results of the hypertension optimal treatment (HOT) randomised trial [J].
Hansson, L ;
Zanchetti, A ;
Carruthers, SG ;
Dahlöf, B ;
Elmfeldt, D ;
Julius, S ;
Ménard, J ;
Rahn, KH ;
Wedel, H ;
Westerling, S .
LANCET, 1998, 351 (9118) :1755-1762
[7]   The J-curve phenomenon revisited [J].
Hedner, Thomas ;
Oparil, Suzanne ;
Narkiewicz, Krzysztof ;
Kjeldsen, Sverre E. .
BLOOD PRESSURE, 2009, 18 (04) :168-170
[8]   SPRINT What Remains Unanswered and Where Do We Go From Here? [J].
Jones, Daniel W. ;
Weatherly, Lyssa ;
Hall, John E. .
HYPERTENSION, 2016, 67 (02) :261-262
[9]   Hypertension optimal treatment (HOT) study - Home blood pressure in treated hypertensive subjects [J].
Kjeldsen, SE ;
Hedner, T ;
Jamerson, K ;
Julius, S ;
Haley, WE ;
Zabalgoitia, M ;
Butt, AR ;
Rahman, SN ;
Hansson, L .
HYPERTENSION, 1998, 31 (04) :1014-1020
[10]  
Kjeldsen SE, 2016, BLOOD PRESSURE, V25