Sera from Patients with Type 2 Diabetes Contain Agonistic Autoantibodies Against G Protein-Coupled Receptors

被引:29
作者
Hempel, P. [1 ]
Karczewski, P. [1 ]
Kohnert, K-D [2 ]
Raabe, J. [3 ]
Lemke, B. [1 ]
Kunze, R. [1 ]
Bimmler, M. [1 ]
机构
[1] ERDE eV, D-13125 Berlin, Germany
[2] Gerhardt Katsch Karlsburg eV, Inst Diabet, Karlsburg, Germany
[3] Asklepios Hosp, Dept Diabetol, Birkenwerder, Germany
关键词
HYPERTENSION; PREECLAMPSIA; ANTIBODIES;
D O I
10.1111/j.1365-3083.2009.02280.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:159 / 160
页数:2
相关论文
共 8 条
[1]   The treatment of hypertension in adult patients with diabetes [J].
Arauz-Pacheco, C ;
Parrott, MA ;
Raskin, P .
DIABETES CARE, 2002, 25 (01) :134-147
[2]   Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection [J].
Dragun, D ;
Müller, DN ;
Bräsen, JH ;
Fritsche, L ;
Nieminen-Kelhä, M ;
Dechend, R ;
Kintscher, U ;
Rudolph, B ;
Hoebeke, J ;
Eckert, D ;
Mazak, I ;
Plehm, R ;
Schönemann, C ;
Unger, T ;
Budde, K ;
Neumayer, HH ;
Luft, FC ;
Wallukat, G .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (06) :558-569
[3]   Direct evidence for a β1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy [J].
Jahns, R ;
Boivin, V ;
Hein, L ;
Triebel, S ;
Angermann, CE ;
Ertl, G ;
Lohse, MJ .
JOURNAL OF CLINICAL INVESTIGATION, 2004, 113 (10) :1419-1429
[4]   alpha(1)-adrenergic receptor antibodies in patients with primary hypertension [J].
Luther, HP ;
Homuth, V ;
Wallukat, G .
HYPERTENSION, 1997, 29 (02) :678-682
[5]   Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor [J].
Wallukat, G ;
Homuth, V ;
Fischer, T ;
Lindschau, C ;
Horstkamp, B ;
Jüpner, A ;
Baur, E ;
Nissen, E ;
Vetter, K ;
Neichel, D ;
Dudenhausen, JW ;
Haller, H ;
Luft, FC .
JOURNAL OF CLINICAL INVESTIGATION, 1999, 103 (07) :945-952
[6]  
Wallukat G, 2001, IN VITRO CELL DEV-AN, V37, P175
[7]   Potential Relevance of α1-Adrenergic Receptor Autoantibodies in Refractory Hypertension [J].
Wenzel, Katrin ;
Haase, Hannelore ;
Wallukat, Gerd ;
Derer, Wolfgang ;
Bartel, Sabine ;
Homuth, Volker ;
Herse, Florian ;
Hubner, Norbert ;
Schulz, Herbert ;
Janczikowski, Marion ;
Lindschau, Carsten ;
Schroeder, Christoph ;
Verlohren, Stefan ;
Morano, Ingo ;
Muller, Dominik N. ;
Luft, Friedrich C. ;
Dietz, Rainer ;
Dechend, Ralf ;
Karczewski, Peter .
PLOS ONE, 2008, 3 (11)
[8]   Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice [J].
Zhou, Cissy C. ;
Zhang, Yujin ;
Irani, Roxanna A. ;
Zhang, Hong ;
Mi, Tiejuan ;
Popek, Edwina J. ;
Hicks, M. John ;
Ramin, Susan M. ;
Kellems, Rodney E. ;
Xia, Yang .
NATURE MEDICINE, 2008, 14 (08) :855-862