Changes of heavy metal concentrations in cross-sections of human femur head

被引:12
作者
Brodziak-Dopierala, Barbara [1 ]
Kwapulinski, Jerzy
Gajda, Zbigniew
Toborek, Jerzy
Bogunia, Maricisz
机构
[1] Silesian Univ Med, Fac Pharm, Dept Toxicol, PL-41200 Sosnowiec, Poland
[2] Town Hosp 2, Siemianowice, Poland
关键词
metals; femur head; cross-section;
D O I
10.1385/BTER:114:1:107
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The concentrations of 12 elements (Ni, Ma, Cr, Cd, Pb, Cu, Fe, Zn, Mg, K, Na, Ca) were determined in cross-sections of human femur heads. The highest concentrations of these elements was found in the cortical bone, and the lowest concentrations occurred in the trabecular bone, with exception of the E cross-section, in which the lowest values were found in articular cartilage. The average concentrations of Na, Ca, K, and Mg were highest in cortical bone and lowest in articular cartilage. Pb was found in higher concentrations in articular cartilage and lowest in trabecular bone, with exception of cross-sections A and E. The Fe contents in the cortical parts were highest in cross-sections A, B, and D. Cu was highest in cross-sections B, C, and D of articular cartilage. These results show that the contents of the selected metals in the femur head varied considerably. As expected, the largest concentrations were found in the outmost part of cross-section E and the lowest in its innermost one, possibly related to mechanical stress.
引用
收藏
页码:107 / 114
页数:8
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