mGlu1 Receptors and downstream signal transduction proteins as therapeutic targets for the treatment of metastatic melanoma

被引：0
|
作者：
Gelb, Tara [1 ]
Pshenichkin, Sergey [1 ]
Hathaway, Hannah A. [1 ]
Grajkowska, Ewa [1 ]
Wolfe, Barry B. [1 ]
Wroblewski, Jarda T. [1 ]
机构：
[1] Georgetown Univ, Washington, DC USA
来源：
CANCER RESEARCH | 2015年 / 75卷
关键词：
D O I：
10.1158/1538-7445.MEL2014-A15
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A15
引用
收藏
页数：1
相关论文
共 21 条
  • [1] mGlu1 Receptors and Downstream Signal Transduction Proteins as Therapeutic Targets for the Treatment of Melanoma
    Gelb, T.
    Pshenichkin, S.
    Hathaway, H.
    Brownell, I.
    Wolfe, B.
    Wroblewski, J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 : S20 - S20
  • [2] Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors
    Werthmann, Ruth C.
    Tzouros, Manuel
    Lamerz, Jens
    Augustin, Angelique
    Fritzius, Thorsten
    Trovo, Luca
    Stawarski, Michal
    Raveh, Adi
    Diener, Catherine
    Fischer, Christophe
    Gassmann, Martin
    Lindemann, Lothar
    Bettler, Bernhard
    NEUROPHARMACOLOGY, 2021, 190
  • [3] The MAP kinase signal transduction pathway: promising therapeutic targets used in the treatment of melanoma
    McClure, Erin
    Carr, Michael J.
    Zager, Jonathan S.
    EXPERT REVIEW OF ANTICANCER THERAPY, 2020, 20 (08) : 687 - 701
  • [4] Malignant melanoma - molecular targets other than signal transduction proteins
    Lorigan, P.
    Margison, G. P.
    ARCHIVES OF DERMATOLOGICAL RESEARCH, 2007, 299 (5-6) : 300 - 300
  • [5] Trametinib: A novel signal transduction inhibitor for the treatment of metastatic cutaneous melanoma
    Chung, Clement
    Reilly, Sean
    AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2015, 72 (02) : 101 - 110
  • [6] Targeting mGlu1 Receptors in the Treatment of Motor and Cognitive Dysfunctions in Mice Modeling Type 1 Spinocerebellar Ataxia
    Liberatore, Francesca
    Antenucci, Nico
    Tortolani, Daniel
    Mascio, Giada
    Fanti, Federico
    Sergi, Manuel
    Battaglia, Giuseppe
    Bruno, Valeria
    Nicoletti, Ferdinando
    Maccarrone, Mauro
    Notartomaso, Serena
    CELLS, 2022, 11 (23)
  • [7] Metabotropic glutamate 5 (mGlu5) receptors may represent viable therapeutic targets for the treatment of alcoholism
    Rorick-Kehn, L. M.
    McKinzie, D. L.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2006, 30 (06) : 131A - 131A
  • [8] Membrane actions of progestins at dopamine type 1-like and GABAA receptors involve downstream signal transduction pathways
    Frye, Cheryl A.
    Walf, Alicia A.
    STEROIDS, 2008, 73 (9-10) : 906 - 913
  • [9] Comparative analyses of downstream signal transduction targets modulated after activation of the AT1 receptor by two β-arrestin-biased agonists
    Santos, Geisa A.
    Duarte, Diego A.
    Parreiras-e-Silva, Lucas T.
    Teixeira, Felipe R.
    Silva-Rochay, Rafael
    Oliveira, Eduardo B.
    Bouvier, Michel
    Costa-Neto, Claudio M.
    FRONTIERS IN PHARMACOLOGY, 2015, 6
  • [10] Signal transduction protein ERK1 and ERK2 are therapeutic targets for the inhibition of retinal angiogenesis.
    Bullard, LE
    Penn, JS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2000, 41 (04) : S140 - S140
123