Rhodium-catalyzed asymmetric ring opening of azabenzonorbornadiene with substituted piperazine nucleophiles

被引：11

作者：

Xie, Lei ^{[1
]}

Yang, Ding Qiao ^{[1
]}

Zhao, Shuang Qi ^{[1
]}

Wang, Huan ^{[1
]}

Liang, Li Hua ^{[1
]}

Luo, Ren Shi ^{[1
]}

机构：

[1] S China Normal Univ, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2007年 / 18卷 / 02期

关键词：

rhodium-catalyzed; asymmetric ring opening; azabenzonorbornadiene;

D O I：

10.1016/j.cclet.2006.12.003

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have developed an asymmetric ring opening reaction of azabenzonorbomadiene with substituted piperazine. By increasing the amount of catalyst (from 2.5 to 5%) and ligands (5 to 10%) as well as addition of ammonium iodide, the products can be obtained in high yield and the reaction time shortened dramatically, but the ee values were rather low. (c) 2006 Ding Qiao Yang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：127 / 129

页数：3

共 12 条

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