EIN2, the central regulator of ethylene signalling, is localized at the ER membrane where it interacts with the ethylene receptor ETR1

被引：117

作者：

Bisson, Melanie M. A. ^{[1
]}

Bleckmann, Andrea ^{[2
]}

Allekotte, Silke ^{[1
]}

Groth, Georg ^{[1
]}

机构：

[1] Univ Dusseldorf, Dept Plant Biochem, D-40225 Dusseldorf, Germany

[2] Univ Dusseldorf, Dept Genet, D-40225 Dusseldorf, Germany

来源：

BIOCHEMICAL JOURNAL | 2009年 / 424卷

关键词：

ethylene insensitive 2 (EIN2); ethylene signalling; fluorescence spectroscopy; membrane protein; plant hormone; protein-protein interaction; PROTEIN SECONDARY STRUCTURE; ENDOPLASMIC-RETICULUM; ARABIDOPSIS; EXPRESSION; FAMILY; RESPONSES; PATHWAY; GENES; CTR1; SET;

D O I：

10.1042/BJ20091102

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Genetic studies have identified the membrane protein EIN2 (ethylene insensitive 2) as a central component of ethylene signalling in Arabidopsis. In addition, EIN2 might take part in multiple hormone signalling pathways and in response to pathogens as demonstrated by recent genetic and biochemical studies. Here we show, by an integrated approach using in vivo and in vitro fluorescence techniques, that EIN2 is localized at the ER (endoplasmic reticulum) membrane where it shows specific interaction with the ethylene receptor protein ETR1.

引用

页码：1 / 6

页数：6

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