Aspergillus niger genomics: Past, present and into the future

被引：148

作者：

Baker, Scott E. ^{[1
]}

机构：

[1] Pacific NW Natl Lab, Fungal Biotechnol Team, Richland, WA 99352 USA

来源：

MEDICAL MYCOLOGY | 2006年 / 44卷

关键词：

Aspergillus niger; genome; wildtype; mutant;

D O I：

10.1080/13693780600921037

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Aspergillus niger is a filamentous ascomycete fungus that is ubiquitous in the environment and has been implicated in opportunistic infections of humans. In addition to its role as an opportunistic human pathogen, A. niger is economically important as a fermentation organism used for the production of citric acid. Industrial citric acid production by A. niger represents one of the most efficient, highest yield bioprocesses in use currently by industry. The genome size of A. niger is estimated to be between 35.5 and 38.5 megabases (Mb) divided among eight chromosomes/linkage groups that vary in size from 3.5-6.6 Mb. Currently, there are three independent A. niger genome projects, an indication of the economic importance of this organism. The rich amount of data resulting from these multiple A. niger genome sequences will be used for basic and applied research programs applicable to fermentation process development, morphology and pathogenicity.

引用

页码：S17 / S21

页数：5

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