Gout: optimizing treatment to achieve a disease cure

被引：29

作者：

Antonio Bernal, Jose ^{[1
]}

Quilis, Neus ^{[1
]}

Andres, Mariano ^{[1
]}

Sivera, Francisca ^{[2
]}

Pascual, Eliseo ^{[1
,3
]}

机构：

[1] Hosp Gen Univ Alicante, Secc Reumatol, Pintor Baeza 12, Alicante 03010, Spain

[2] Hosp Gen Univ Elda, Secc Reumatol, Alicante, Spain

[3] Univ Miguel Hernandez, Dept Med Reumatol, Alicante, Spain

来源：

THERAPEUTIC ADVANCES IN CHRONIC DISEASE | 2016年 / 7卷 / 02期

关键词：

allopurinol; colchicine; gout; monosodium urate crystals; uric acid; EVIDENCE-BASED RECOMMENDATIONS; RANDOMIZED CONTROLLED-TRIAL; URIC-ACID METABOLISM; DOUBLE-BLIND; SYNOVIAL-FLUID; CLINICAL-TRIAL; TRIAMCINOLONE ACETONIDE; CONVENTIONAL TREATMENT; ALLOPURINOL THERAPY; INTERCRITICAL GOUT;

D O I：

10.1177/2040622315618393

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Gout is one of the most common inflammatory arthritides. The disease is due to the deposition of monosodium urate crystals. These deposits are reversible with proper treatment, suggesting that gout is a curable disease. The main aim in gout is to lower serum uric acid levels to a pre-established target; there are different urate-lowering drugs (xanthine oxidase inhibitors, uricosurics and uricases) through which this can be achieved. Proper treatment of gout also involves correct management of acute flares and their prevention. To ensure treatment adherence it is necessary to explain to the patient what the objectives are.

引用

页码：135 / 144

页数：10

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