Gastrointestinal zygomycosis caused by Mucor indicus in a patient with acute traumatic brain injury

被引:20
作者
Deja, Maria
Wolf, Steffen
Weber-Carstens, Steffen
Lehmann, Thomas-Nicolas
Adler, Andreas
Ruhnke, Markus
Tintelnot, Kathrin [1 ]
机构
[1] Robert Koch Inst, D-13353 Berlin, Germany
[2] Univ Med, Dept Anesthesiol & Intens Care Med, Charite, Berlin, Germany
[3] Univ Med, Dept Neurosurg, Charite, Berlin, Germany
[4] Univ Med, Div Hepatol Gastroenterol Endocrinol & Metab, Charite, Berlin, Germany
[5] Univ Med, Dept Med, Div Oncol Hematol, Charite Mitte, Berlin, Germany
关键词
zygomycosis; gastrointestinal; Mucor indicus; liposomal amphotericin B; trauma;
D O I
10.1080/13693780600803888
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We report a gastrointestinal infection caused by Mucor indicus in a patient with severe head injuries. Monotherapy with high-dose liposomal amphotericin B successfully eradicated the mucormycosis. Nevertheless, subsequently a hemicolectomy was necessary due to recurrent bleeding from a deep ulcer. Mucor indicus is an uncommon fungal pathogen, typically found in starters used for food fermentation. Reviewing other reports on Mucor indicus infections, primary gastrointestinal manifestations seem to be typical and indicate an oral route of infection.
引用
收藏
页码:683 / 687
页数:5
相关论文
共 20 条
[1]   Fungemia secondary to gastrointestinal Mucor indicus infection [J].
Aboltins, CA ;
Pratt, WAB ;
Solano, TR .
CLINICAL INFECTIOUS DISEASES, 2006, 42 (01) :154-155
[2]  
[Anonymous], 1990, PCR PROTOCOLS, DOI DOI 10.1016/B978-0-12-372180-8.50042-1
[3]   Gastrointestinal zygomycosis: two case reports [J].
Azadeh, B ;
McCarthy, DO ;
Dalton, A ;
Campbell, F .
HISTOPATHOLOGY, 2004, 44 (03) :298-300
[4]  
de Hoog G.S., 2000, ATLAS CLIN FUNGI, VSecond
[5]  
Frater JL, 2001, ARCH PATHOL LAB MED, V125, P375
[6]   Interferon-γ and granulocyte-macrophage colony-stimulating factor augment the activity of polymorphonuclear leukocytes against medically important Zygomycetes [J].
Gil-Lamaignere, C ;
Simitsopoulou, M ;
Roilides, E ;
Maloukou, A ;
Winn, RM ;
Walsh, TJ .
JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (07) :1180-1187
[7]   GASTROINTESTINAL ASPERGILLOSIS AND ZYGOMYCOSIS OF CATTLE [J].
JENSEN, HE ;
OLSEN, SN ;
AALBAEK, B .
VETERINARY PATHOLOGY, 1994, 31 (01) :28-36
[8]   Effect of high pressure homogenization and papain on the preparation of autolysed yeast extract [J].
C. Verduyn ;
A. Suksomcheep ;
M. Suphantharika .
World Journal of Microbiology and Biotechnology, 1999, 15 (1) :57-63
[9]   Nonfatal gastric mucormycosis in a renal transplant recipient [J].
Martinez, EJ ;
Cancio, MR ;
Sinnott, JT ;
Vincent, AL ;
Brantley, SG .
SOUTHERN MEDICAL JOURNAL, 1997, 90 (03) :341-344
[10]   Mucor indicus necrotizing fasciitis [J].
Mata-Essayag, S ;
Magaldi, S ;
de Capriles, CH ;
Henao, L ;
Garrido, L ;
Pacillo, V .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2001, 40 (06) :406-408