First example of a total axial to centered chirality transfer in the [2+2+2] cycloadditions of allenediynes

被引：0

作者：

Buisine, O ^{[1
]}

Aubert, C ^{[1
]}

Malacria, M ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, Lab Chim Organ Synth, F-75252 Paris, France

来源：

SYNTHESIS-STUTTGART | 2000年 / 07期

关键词：

alkynes; allenes; chirality; cycloadditions; cobalt;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cobalt-mediated [2+2+2] cycloaddition of allene-diynes bearing a phosphine oxide group at one alkyne terminus is a completely regio-, chemo- and diastereoselective high yielding process. Moreover. a total transfer of chiral information from axial to centered chirality is evident, which makes this reaction a new and powerful tool for the preparation of enantiomerically enriched tricyclic derivatives.

引用

页码：985 / 989

页数：5

共 35 条

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