Nuclear envelope dynamics in oocytes:: from germinal vesicle breakdown to mitosis

被引:37
|
作者
Lénárt, P [1 ]
Ellenberg, J [1 ]
机构
[1] European Mol Biol Lab, Gene Express & Cell Biol Biophys Programmes, D-69117 Heidelberg, Germany
关键词
D O I
10.1016/S0955-0674(02)00011-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
We have recently gained new insight into the mechanisms involved in nuclear envelope breakdown, the irreversible step that commits a cell to the M phase. Results from mammalian cell and starfish oocyte studies suggest that mechanical forces of the cytoskeleton, as well as biochemical disassembly of nuclear envelope protein complexes, play important roles in this process.
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页码:88 / 95
页数:8
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