Methylsulfonylmethane observed by in vivo proton magnetic resonance spectroscopy in a 5-year-old child with developmental disorder: Effects of dietary supplementation

被引:12
作者
Cecil, KM
Lin, A
Ross, BD
Egelhoff, JC
机构
[1] Univ Cincinnati, Childrens Hosp, Ctr Med, Dept Radiol, Cincinnati, OH 45229 USA
[2] Huntington Med Res Inst, MR Spectroscopy Unit, Pasadena, CA USA
关键词
magnetic resonance spectroscopy methylsulfonylmethane; health food supplements; human brain metabolism;
D O I
10.1097/00004728-200209000-00026
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Proton magnetic resonance spectroscopy (MRS) revealed a distinct resonance at 3.15 ppm in the brain of a 5-year-old male diagnosed with autism. The resonance assignment is attributable to ingestion of methylsulfonylmethane (MSM) as a dietary supplement. Glucosamine with MSM is marketed as a source of dietary sulfur and treatment of joint pain. Recognition of this chemical on brain proton MRS as an exogenous compound is necessary to avoid confusion as a pathologic metabolite of pediatric metabolic disease.
引用
收藏
页码:818 / 820
页数:3
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