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Univ Hosp Greifswald, Dept Internal Med B, Cardiol, Pneumol,Infect Dis,Intens Care Med, F Sauerbruchstr, D-17475 Greifswald, Germany Univ Hosp Greifswald, Dept Internal Med B, Cardiol, Pneumol,Infect Dis,Intens Care Med, F Sauerbruchstr, D-17475 Greifswald, Germany