Determination of acetaminophen by square wave voltammetry at a gold electrode modified by 4-amino-2-mercaptopyrimidine self-assembled monolayers

被引：40

作者：

Jia, Li ^{[1
]}

Zhang, X. -H. ^{[1
]}

Li, Q. ^{[1
]}

Wang, S. -F. ^{[1
]}

机构：

[1] Hubei Univ, Fac Chem & Mat Sci, Wuhan 430062, Peoples R China

来源：

JOURNAL OF ANALYTICAL CHEMISTRY | 2007年 / 62卷 / 03期

关键词：

D O I：

10.1134/S1061934807030136

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A 4-Amino-2-mercaptopyrimidine self-assembled monolayer (AMP SAMs/Au) modified gold electrode was prepared. The electrochemical behavior of acetaminophen on the AMP SAMs/Au was studied in Britton-Robinson (BR) buffer solution. Compared to a bare gold electrode, the modified electrode exhibits a significant enhancement in the oxidation current response for acetaminophen. The modified electrode was used for the determination of acetaminophen by square wave voltammetry. The oxidation current increased linearly with the concentration of acetaminophen in the range of 2.0 x 10(-6)-4.0 x 10(-3) M. The modified electrode made it possible to eliminate the interference of dopamine (DA), brucine, epinephrine (EP), and norepinephrine (NE). The practical analytical utility was illustrated by the determination of acetaminophen in a commercially available drug.

引用

页码：266 / 269

页数：4

共 20 条

[1]

BARD AJ, 1980, ELECTROCHEMICAL METH

[2]

Ding S.J., 1991, CHEM J CHINESE U, V12, P598

[3] Investigation and comparison of the electrochemical behavior of some organic and biological molecules at various conducting polymer electrodes [J].

Erdogdu, G ;

Karagozler, AE .

TALANTA, 1997, 44 (11) :2011-2018

[4] Wettability of transition metal oxide surfaces [J].

Feng, AG ;

McCoy, BJ ;

Munir, ZA ;

Cagliostro, D .

MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING, 1998, 242 (1-2) :50-56

[5] Electrochemistry of electropolymerized tetra(p-aminophenyl)porphyrin nickel film electrode and catalytic oxidation of acetaminophen [J].

Huang, SS ;

Tang, H ;

Li, BF .

MIKROCHIMICA ACTA, 1998, 128 (1-2) :37-42

[6]

JIA L, 2005, CHIN J APPL CHEM, V2, P172

[7]

KISSINGER PT, 1983, J CHEM EDUC, V60, P702, DOI 10.1021/ed060p702

[8]

LIU CY, 1998, CHIN J ANAL TEST TEC, V12, P209

[9] Liver death and regeneration in paracetamol toxicity [J].

McGregor, A ;

More, LJ ;

Simpson, KJ ;

Harrison, DJ .

HUMAN & EXPERIMENTAL TOXICOLOGY, 2003, 22 (04) :221-227

[10]

MINER DJ, 1981, ANAL CHEM, V53, P2258, DOI 10.1021/ac00237a029

← 1 2 →