Electrospinning of Novel Poly(ester amide)s

被引：12
作者：
Garg, Priya [1 ,2 ]
Klee, Doris [1 ,2 ]
Keul, Helmut [1 ,2 ]
Moeller, Martin [1 ,2 ]
机构：
[1] RWTH Aachen eV, Inst Tech & Macromol Chem, D-52056 Aachen, Germany
[2] RWTH Aachen eV, DWI, D-52056 Aachen, Germany
来源：
MACROMOLECULAR MATERIALS AND ENGINEERING | 2009年 / 294卷 / 10期
关键词：
electrospinning; fibers; microstructure; poly(ester amide)s; synthesis; RING-OPENING POLYMERIZATION; BLOCK-COPOLYMERS; DRUG-DELIVERY; NANOFIBERS; FIBERS; DIAMETER; POLYMERS; SEGMENTS; DIOLS;
D O I：
10.1002/mame.200900090
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Novel PEAs derived from 1,4-butanediol, dimethyl adipate and a preformed alpha,omega-amino alcohol were synthesised and successfully electrospun from solution. The effects of increasing the ratio of amide/ester groups in the copolymer, polymer concentration, solvent mixtures and applied voltage on fibre morphology and diameter were investigated. The obtained fibres (diameter 180-450 nm) were randomly oriented. The fibre quality and homogeneity increased with increasing amide concentration. The solvent mixture CHCl3/HCOOH gave the best electrospinning results. The ultra-fine fibres were characterised using SEM, DSC and FT-IR, showing that the electrospun fibres are amorphous as compared to the pristine samples. These fibres are potential candidates for use as scaffolds in tissue engineering.
引用
收藏
页码：679 / 690
页数：12
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