Asymmetric allylic oxidation of cycloalkenes using a tridentate tris(oxazoline) ligand as a chiral auxiliary

被引：84

作者：

Kohmura, Y ^{[1
]}

Katsuki, T ^{[1
]}

机构：

[1] Kyushu Univ 33, Grad Sch Sci, Dept Mol Chem, Higashi Ku, Fukuoka 8128581, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 20期

关键词：

tris(oxazoline) ligand; asymmetric allylic oxidation;

D O I：

10.1016/S0040-4039(00)00522-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A tridentate tris(oxazoline) ligand (4b) was found to be an efficient chiral auxiliary for copper-mediated asymmetric allylic oxidation (Kharash-Sosnovsky reaction) of cycloalkenes. Regardless of the ring size of the substrate, the reaction examined showed good enantioselectivity higher than 81% ee. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3941 / 3945

页数：5

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