Protein structure prediction in the postgenomic era

被引：50
作者：
Jones, DT [1 ]
机构：
[1] Brunel Univ, Dept Biol Sci, Uxbridge UB8 3PH, Middx, England
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 2000年 / 10卷 / 03期
关键词：
D O I：
10.1016/S0959-440X(00)00099-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
As the number of completely sequenced genomes rapidly increases, the postgenomic problem of gene function identification becomes ever more pressing. Predicting the structures of proteins encoded by genes of interest is one possible means to glean subtle clues as to the functions of these proteins. There are limitations to this approach to gene identification and a survey of the expected reliability of different protein structure prediction techniques has been undertaken.
引用
收藏
页码：371 / 379
页数：9
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