A mesothelioma epidemic in Cappadocia: scientific developments and unexpected social outcomes

被引:186
作者
Carbone, Michele
Emri, Salih
Dogan, A. Umran
Steele, Ian
Tuncer, Murat
Pass, Harvey I.
Baris, Y. Izzettin
机构
[1] Canc Res Ctr Hawaii, Thorac Oncol Program, Honolulu, HI 96816 USA
[2] Hacettepe Univ, Dept Pulm Med, TR-06532 Ankara, Turkey
[3] Hacettepe Univ, Dept Hematol & Oncol, TR-06532 Ankara, Turkey
[4] Ankara Univ, Dept Geol Engn, TR-06100 Ankara, Turkey
[5] Univ Iowa, Dept Chem & Biochem Engn, Iowa City, IA 52242 USA
[6] Univ Chicago, Dept Geophys Sci, Chicago, IL 60637 USA
[7] NYU, Dept Cardiothorac Surg, New York, NY 10016 USA
关键词
D O I
10.1038/nrc2068
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In Cappadocia, Turkey, an unprecedented mesothelioma epidemic causes 50% of all deaths in three small villages. Initially linked solely to the exposure to a fibrous mineral, erionite, recent studies by scientists from Turkey and the United States have shown that erionite causes mesothelioma mostly in families that are genetically predisposed to mineral fibre carcinogenesis. This manuscript reports, through the eyes of one of the researchers, the resulting scientific advances that have come from these studies and the social improvements that were brought about by both the scientists and members of the Turkish Government.
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收藏
页码:147 / 154
页数:9
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