Infliximab is effective in the treatment of ulcerative colitis with dermatomyositis: A case report

被引：6

作者：

Huang, Bin-Bin ^{[1
]}

Han, Li-Chun ^{[1
]}

Liu, Geng-Feng ^{[1
]}

Lv, Xiao-Dan ^{[2
]}

Gu, Guang-Li ^{[1
]}

Li, Shi-Quan ^{[1
]}

Chen, Lan ^{[1
]}

Wang, Hui-Qin ^{[1
]}

Zhan, Ling-Ling ^{[2
]}

Lv, Xiao-Ping ^{[1
]}

机构：

[1] Guangxi Med Univ, Affiliated Hosp 1, Dept Gastroenterol, 6 Shuangyong Rd, Nanning 530021, Guangxi Zhuang, Peoples R China

[2] Guangxi Med Univ, Affiliated Hosp 1, Dept Clin Lab, Nanning 530021, Guangxi Zhuang, Peoples R China

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2020年 / 26卷 / 46期

基金：

中国国家自然科学基金;

关键词：

Ulcerative colitis; Dermatomyositis; Extraintestinal manifestation; Infliximab; Mesalazine; Case report; INFLAMMATORY-BOWEL-DISEASE; EXTRAINTESTINAL MANIFESTATIONS; ADULT DERMATOMYOSITIS; THERAPY; CLASSIFICATION; IMMUNOGLOBULIN; CONSENSUS; EFFICACY;

D O I：

10.3748/wjg.v26.i46.7425

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

BACKGROUND Joint, skin, oral cavity, and eye lesions are the most common extraintestinal manifestations of ulcerative colitis that can occur before or after its onset. The cases of ulcerative colitis with dermatomyositis (DM) are rare. In this study, we report a rare case of ulcerative colitis with DM that was effectively treated with infliximab. CASE SUMMARY The patient was a 57-year-old female with a 2-year history of DM. The patient was admitted to hospital with abdominal pain, diarrhea, and blood in stool lasting for more than 2 mo. Colonoscopy revealed multiple erosions and ulcers in the entire colon and rectum. Pathological sections showed chronic inflammatory cell infiltration, especially neutrophil infiltration, in the colonic mucosa; therefore, the patient was diagnosed with ulcerative colitis. Preparations of 5-aminosalicylic acid was added to her treatment based on the original treatment for DM, but its effect was unsatisfactory. The patient's discomfort was relieved after infliximab treatment. CONCLUSION Infliximab can improve DM in the treatment of ulcerative colitis. Specialists need to raise awareness about patients with inflammatory bowel disease who have rare extraintestinal manifestations.

引用

页码：7425 / 7435

页数：11