Antimicrobial intermediates of the general phenylpropanoid and lignin specific pathways

被引：121

作者：

Barber, MS ^{[1
]}

McConnell, VS ^{[1
]}

DeCaux, BS ^{[1
]}

机构：

[1] Univ Southampton, Sch Biol Sci, Southampton SO16 7PX, Hants, England

来源：

PHYTOCHEMISTRY | 2000年 / 54卷 / 01期

关键词：

antimicrobial activity; hydroxycinnamaldehydes; hydroxycinnamyl alcohols; hydroxycinnamic acids; lignin;

D O I：

10.1016/S0031-9422(00)00038-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The minimum inhibitory concentration (MIC) of the major intermediates of the general phenylpropanoid and lignin specific pathways of plants were determined employing a range of yeasts and bacteria. Of the three main classes of compounds tested, the hydroxycinnamaldehydes were the most effective, possessing notable antifungal and antibacterial activity. Determination of the minimum killing concentration (MKC) of the hydroxycinnamaldehydes revealed MIC/MKC ratios suggesting these compounds to be fungicidal, but not bactericidal, in their mode of action. In contrast, the hydroxycinnamic acids and hydroxycinnamyl alcohols possessed little antimicrobial activity, with the exception of the hydroxycinnamic acids, which were antibacterial. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：53 / 56

页数：4

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