In silico cell II.: information sources for modeling Escherichia coli metabolic pathways

被引：0

作者：

Khlebodarova, T. M. ^{[1
]}

Ananko, E. A. ^{[1
]}

Nedosekina, E. A. ^{[1
]}

Podkolodnaya, O. A. ^{[1
]}

Poplavsky, A. S. ^{[1
]}

Smirnova, O. G. ^{[1
]}

Ibragimova, S. S. ^{[1
]}

Mishchenko, E. L. ^{[1
]}

Stepanenko, I. L. ^{[1
]}

Ignatieva, E., V ^{[1
]}

Proskura, A. L. ^{[1
]}

Nishio, Y. ^{[2
]}

Imakumi, A. ^{[2
]}

Usuda, Y. ^{[2
]}

Matsui, K. ^{[2
]}

Podkolodny, N. L. ^{[1
]}

Kolchanov, N. A. ^{[1
]}

机构：

[1] SB RAS, Inst Cytol & Genet, Novosibirsk 630090, Russia

[2] Ajinomoto Co Inc, Inst Life Sci, Kawasaki, Kanagawa, Japan

来源：

PROCEEDINGS OF THE FIFTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE, VOL 2 | 2006年

关键词：

database; transcription; expression; gene networks; metabolism; constants; dynamics; kinetics; modeling; functional parameters; Escherichia coli;

D O I：

暂无

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Motivation: Development of an in silico cell, a computer resource for modeling and analysis of physiological processes is an urgent task of systems biology and computational biology. This field of inquiry demands development of software for accumulation and analysis of information on operation of the cell as an integrated system. Results: We developed three information sources for computer modeling of manifold processes of E. coli: 1) EcoTRRD database designed for description of structure and function of regulatory regions of E. coli genes; 2) EcoGeneNet database was developed for description of metabolic networks in E. coli; 3) EcoKiNET database allows to accumulate the quantitative information about the dynamics on biosynthesis of amino acids, nucleotides, and sugars in E. coli.

引用

页码：19 / +

页数：2

共 6 条

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