Statins and Intracerebral Hemorrhage: Potential Mechanisms

被引:1
作者
Eisa-Beygi, Shahram [1 ]
El-Rass, Suzan [2 ,3 ,4 ]
机构
[1] ACECR, Royan Inst Stem Cell Biol & Technol, Cell Sci Res Ctr, Dept Stem Cells & Dev Biol, Tehran, Iran
[2] St Michaels Hosp, Keenan Res Ctr Biomed Sci, 30 Bond St, Toronto, ON M5B 1W8, Canada
[3] St Michaels Hosp, Li Ka Shing Knowledge Inst, 30 Bond St, Toronto, ON M5B 1W8, Canada
[4] Univ Toronto, Inst Med Sci, Toronto, ON, Canada
关键词
CDC42; STABILITY;
D O I
10.1016/j.jstrokecerebrovasdis.2015.11.002
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:496 / 496
页数:1
相关论文
共 10 条
[1]   Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac [J].
Birukov, KG ;
Bochkov, VN ;
Birukova, AA ;
Kawkitinarong, K ;
Rios, A ;
Leitner, A ;
Verin, AD ;
Bokoch, GM ;
Leitinger, N ;
Garcia, JGN .
CIRCULATION RESEARCH, 2004, 95 (09) :892-901
[2]   Cdc42 regulates adherens junction stability and endothelial permeability by inducing α-catenin interaction with the vascular endothelial cadherin complex [J].
Broman, MT ;
Kouklis, P ;
Gao, XP ;
Ramchandran, R ;
Neamu, RF ;
Minshall, RD ;
Malik, AB .
CIRCULATION RESEARCH, 2006, 98 (01) :73-80
[3]   A Call for Rigorous Study of Statins in Resolution of Cerebral Cavernous Malformation Pathology [J].
Eisa-Beygi, Shahram ;
Wen, Xiao-Yan ;
Macdonald, R. Loch .
STROKE, 2014, 45 (06) :1859-1861
[4]   The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway [J].
Eisa-Beygi, Shahram ;
Hatch, Gary ;
Noble, Sandra ;
Ekker, Marc ;
Moon, Thomas W. .
DEVELOPMENTAL BIOLOGY, 2013, 373 (02) :258-266
[5]   Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction [J].
Faurobert, Eva ;
Albiges-Rizo, Corinne .
FEBS JOURNAL, 2010, 277 (05) :1084-1096
[6]   Guidelines for the Management of Spontaneous Intracerebral Hemorrhage A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association [J].
Hemphill, J. Claude, III ;
Greenberg, Steven M. ;
Anderson, Craig S. ;
Becker, Kyra ;
Bendok, Bernard R. ;
Cushman, Mary ;
Fung, Gordon L. ;
Goldstein, Joshua N. ;
Macdonald, R. Loch ;
Mitchell, Pamela H. ;
Scott, Phillip A. ;
Selim, Magdy H. ;
Woo, Daniel .
STROKE, 2015, 46 (07) :2032-2060
[7]   Cdc42-and rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling [J].
Koh, Wonshill ;
Mahan, Rachel D. ;
Davis, George E. .
JOURNAL OF CELL SCIENCE, 2008, 121 (07) :989-1001
[8]   Cdc42 regulates the restoration of endothelial barrier function [J].
Kouklis, P ;
Konstantoulaki, M ;
Vogel, S ;
Broman, M ;
Malik, AB .
CIRCULATION RESEARCH, 2004, 94 (02) :159-166
[9]   Are statins to be STASHed in subarachnoid haemorrhage? [J].
Macdonald, R. Loch .
LANCET NEUROLOGY, 2014, 13 (07) :639-641
[10]   Meta-analysis of Statin Use for the Acute Therapy of Spontaneous Intracerebral Hemorrhage [J].
Perez, J. Humberto Tapia ;
Yildiz, O. Can ;
Schneider, Thomas ;
Nimsky, Christopher .
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2015, 24 (11) :2521-2526