A meta-analysis of human papillomavirus prevalence and types among Iranian women with normal cervical cytology, premalignant lesions, and cervical cancer

被引:20
作者
Salavatiha, Zahra [1 ]
Farahmand, Mohammad [1 ]
Shoja, Zabihollah [2 ]
Jalilvand, Somayeh [1 ]
机构
[1] Univ Tehran Med Sci, Sch Publ Hlth, Dept Virol, Tehran 14155, Iran
[2] Pasteur Inst Iran, Dept Virol, Tehran, Iran
关键词
cervical cancer; genotypes; human papillomavirus; Iran; prevalence; RISK HUMAN-PAPILLOMAVIRUS; HPV INFECTION; INTRAEPITHELIAL NEOPLASIA; PAP-SMEAR; WORLDWIDE; ASSOCIATION; ATTRIBUTION; EXPRESSION; GENOTYPES; VACCINES;
D O I
10.1002/jmv.26928
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In this study, all data from Iran on human papillomavirus (HPV) prevalence and types among women with normal cervical cytology, premalignant lesions, and cervical cancer were obtained and pooled. The overall HPV prevalence was found to be 9% in women with a normal cervix, 55% in atypical squamous cells of undetermined significance or atypia cases, 58% and 69% in women with low and high grade squamous intraepithelial lesions, respectively, and 81% among women with invasive cervical cancer. In all of the studied groups, HPV 16 was the most common HPV type, followed by HPV 18. In conclusion, this meta-analysis revealed that it will be beneficial if current HPV vaccines are integrated into the national vaccination programs of Iran.
引用
收藏
页码:4647 / 4658
页数:12
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