Acute pulmonary involvement by paracoccidiodomycosis disease immediately after kidney transplantation: Case report and literature review

被引:10
作者
Radisic, Marcelo V. [1 ]
Linares, Laura [1 ]
Afeltra, Javier [2 ,3 ]
Pujato, Natalia [1 ]
Vitale, Roxana G. [2 ,4 ]
Bravo, Martin [1 ]
Dotta, Ana C. [5 ]
Casadei, Domingo H. [5 ]
机构
[1] Inst Nefrol Nephrol, Dept Infect Dis, Buenos Aires, DF, Argentina
[2] Hosp JM Ramos Mejia, Parasitol Unit, Mycol, Unidad Parasitol Micol, Buenos Aires, DF, Argentina
[3] Univ Buenos Aires, Fac Med, Dept Microbiol, Buenos Aires, DF, Argentina
[4] Consejo Nacl Invest Cient & Tecn, Buenos Aires, DF, Argentina
[5] Inst Nefrol Nephrol, Kidney Transplant Unit, Dept Transplantat, Buenos Aires, DF, Argentina
关键词
endemic mycosis; kidney transplantation; liposomal amphotericin B; paracoccidioidomycosis; pulmonary disease; HUMAN-IMMUNODEFICIENCY-VIRUS; PARACOCCIDIOIDOMYCOSIS; INFECTION; DIAGNOSIS;
D O I
10.1111/tid.12655
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Paracoccidioides brasiliensis is the cause of paracoccidioidomycosis, one of the most important systemic mycoses in Latin America. Human disease has been observed in a limited geographic and ecological niche, and it is attributed to exposure to the fungus in soil. Most primary infections are subclinical, as the infection is contained by the host mainly through cell-mediated immune response. However, as the fungus has the ability to survive in a dormant state for long periods, an impairment of the immune response may lead to reactivation and clinical disease. Surprisingly, paracoccidioidomycosis has rarely been reported in transplanted patients. The aim of this communication is to report a case occurring in a kidney recipient in an acute clinical form immediately after transplantation, and to review the available information on previously reported cases.
引用
收藏
页数:6
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