The most versatile of all reactive intermediates?

被引：38

作者：

Flashman, Emily ^{[1
]}

Schofield, Christopher J. ^{[1
]}

机构：

[1] Univ Oxford, Chem Res Lab, Oxford OX1 3TA, England

来源：

NATURE CHEMICAL BIOLOGY | 2007年 / 3卷 / 02期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1038/nchembio0207-86

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The iron( II)- and 2- oxoglutarate- dependent oxygenases catalyze varied oxidative reactions. Spectroscopic analyses on the catalytic cycle of the chlorinating enzyme CytC3 reveal the presence of chloride - iron( IV) - oxo complexes, expanding the scope of chemistry known to be catalyzed by non- heme iron- oxo species.

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页码：86 / 87

页数：2

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