Easy Ruthenium-Catalysed Oxidation of Primary Amines to Nitriles under Oxidant-Free Conditions

被引：30

作者：

Achard, Thierry ^{[1
]}

Egly, Julien ^{[1
]}

Sigrist, Michel ^{[1
]}

Maisse-Francois, Aline ^{[1
]}

Bellemin-Laponnaz, Stephane ^{[1
]}

机构：

[1] Univ Strasbourg, Dept Mat Organ, IPCMS, CNRS UMR 7504, 23 Rue Loess,BP 43, F-67034 Strasbourg 2, France

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2019年 / 25卷 / 58期

关键词：

acceptorless dehydrogenation; dehydrogenation; homogenous catalysis; nitrile; ruthenium; DEHYDROGENATION; COMPLEXES; CONVERSION;

D O I：

10.1002/chem.201902557

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A dehydrogenation of primary amine to give the corresponding nitrile under oxidant- and base-free conditions catalysed by simple [Ru(p-cym)Cl-2](2) with no extra ligand is reported. The system is highly selective for alkyl amines, whereas benzylamine derivatives gave the nitrile product together with the imine in a ratio ranging from 14:1 to 4:1 depending on the substrate. Preliminary mechanistic investigations have been performed to identify the key factors that govern the selectivity.

引用

页码：13271 / 13274

页数：4

共 43 条

[1] The catalytic activity of a cyclometalated ruthenium(III) complex for aerobic oxidative dehydrogenation of benzylamines [J].